[HTML][HTML] Distinct neutralizing antibody escape of SARS-CoV-2 Omicron subvariants BQ. 1, BQ. 1.1, BA. 4.6, BF. 7 and BA. 2.75. 2
P Qu, JP Evans, J Faraone, YM Zheng, C Carlin… - Biorxiv, 2022 - ncbi.nlm.nih.gov
Continued evolution of SARS-CoV-2 has led to the emergence of several new Omicron
subvariants, including BQ. 1, BQ. 1.1, BA. 4.6, BF. 7 and BA. 2.75. 2. Here we examine the …
subvariants, including BQ. 1, BQ. 1.1, BA. 4.6, BF. 7 and BA. 2.75. 2. Here we examine the …
[HTML][HTML] An infectious SARS-CoV-2 B. 1.1. 529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies
… antibody-bound SARS-CoV-2 spike or RBD structures published in the RCSB Protein Data
Bank (PDB) (Fig. 1c–k). Although every antibody … 1.1.529 for antibody neutralization, we used …
Bank (PDB) (Fig. 1c–k). Although every antibody … 1.1.529 for antibody neutralization, we used …
Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain
KG Nabel, SA Clark, S Shankar, J Pan, LE Clark… - Science, 2021 - science.org
… the SARS-CoV spike protein to isolate a neutralizing antibody from … N-linked glycan acquisition
by the SARS-CoV-2 RBD confers … of escape variants as SARS-CoV-2 adapts to humans. …
by the SARS-CoV-2 RBD confers … of escape variants as SARS-CoV-2 adapts to humans. …
[HTML][HTML] Neutralising antibodies in Spike mediated SARS-CoV-2 adaptation
… of different replication sites could allow a better understanding of SARS-CoV-2 population
genetics and enable prediction of escape variants following antibody based therapies. …
genetics and enable prediction of escape variants following antibody based therapies. …
[HTML][HTML] Rapid escape of new SARS-CoV-2 Omicron variants from BA. 2-directed antibody responses
… to escape the antibody response produced by vaccines or severe acute respiratory syndrome
coronavirus 2 (SARS-CoV… We describe a panel of 25 potent monoclonal antibodies (mAbs) …
coronavirus 2 (SARS-CoV… We describe a panel of 25 potent monoclonal antibodies (mAbs) …
[HTML][HTML] Mutational escape from the polyclonal antibody response to SARS-CoV-2 infection is largely shaped by a single class of antibodies
… of anti-RBD antibodies with high-resolution structures. We compare the antibody-escape maps
to … plasma from individuals from whom some of the antibodies were isolated. The plasma-…
to … plasma from individuals from whom some of the antibodies were isolated. The plasma-…
[HTML][HTML] Evidence of escape of SARS-CoV-2 variant B. 1.351 from natural and vaccine-induced sera
… potential for immune escape. Here, … escape from monoclonal antibody neutralization largely
driven by E484K, although K417N and N501Y act together against some important antibody …
driven by E484K, although K417N and N501Y act together against some important antibody …
[HTML][HTML] SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms
… SARS-CoV-2 neutralizing antibodies we isolated from a healthy COVID-19 convalescent
donor. Resistance extends to the polyclonal serum immunoglobulins of four out of four healthy …
donor. Resistance extends to the polyclonal serum immunoglobulins of four out of four healthy …
[HTML][HTML] Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape
… antibodies with activity against emergent variants. To determine how SARS-CoV-2 might
escape these antibodies, … selection by 40 broadly neutralizing antibodies. We identify numerous …
escape these antibodies, … selection by 40 broadly neutralizing antibodies. We identify numerous …
[HTML][HTML] SARS-CoV-2 501Y. V2 variants lack higher infectivity but do have immune escape
Q Li, J Nie, J Wu, L Zhang, R Ding, H Wang, Y Zhang… - Cell, 2021 - cell.com
… to monoclonal antibodies, to SARS-CoV-2 … for SARS-CoV-2-susceptible human cell lines;
however, the 501Y.V2 variants were less susceptible to the neutralizing activity of antibodies …
however, the 501Y.V2 variants were less susceptible to the neutralizing activity of antibodies …