Understanding neutralising antibodies against SARS-CoV-2 and their implications in clinical practice

NYL Pang, ASR Pang, VT Chow, DY Wang - Military Medical Research, 2021 - Springer
… of IgA, IgM and IgG antibodies, and we explore their roles in neutralising SARS-CoV-2, their
… Furthermore, we also review the applications of neutralising antibodies in the clinical setting…

SARS-CoV-2 spike E484K mutation reduces antibody neutralisation

S Jangra, C Ye, R Rathnasinghe, D Stadlbauer… - The Lancet …, 2021 - thelancet.com
… This approach will result in lower neutralising antibody titres. Our data suggest that lower
neutralising antibody titres might be problematic in the context of newly emerging SARS-CoV-2 …

Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study

WN Chia, F Zhu, SWX Ong, BE Young, SW Fong… - The Lancet …, 2021 - thelancet.com
… of protective immunity and longevity of neutralising antibodies for SARS-CoV-2. We aimed
to investigate the peak levels and dynamics of neutralising antibody waning and IgG avidity …

Prevalence of neutralising antibodies against SARS-CoV-2 in acute infection and convalescence: A systematic review and meta-analysis

HR Savage, VS Santos, T Edwards… - PLoS neglected …, 2021 - journals.plos.org
… infections have detectable neutralising antibodies. In this … former SARS-CoV-2 infections
who develop neutralising antibodies, … with SARS-CoV-2 infection have detectable neutralising

Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis

D Cromer, M Steain, A Reynaldi, TE Schlub… - The Lancet …, 2022 - thelancet.com
… vitro neutralisation and clinical protection to understand the loss of neutralisation to existing
SARS-CoV… relating in-vitro neutralisation to protection (parameterised on data from ancestral …

[HTML][HTML] Neutralising antibodies in Spike mediated SARS-CoV-2 adaptation

SA Kemp, DA Collier, R Datir, IATM Ferreira, S Gayed… - MedRxiv, 2020 - ncbi.nlm.nih.gov
… , this raises the theoretical possibility of virus escape, particularly in immunocompromised …
Here we report chronic SARS-CoV-2 with reduced sensitivity to neutralising antibodies in an …

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

D Planas, N Saunders, P Maes, F Guivel-Benhassine… - Nature, 2022 - nature.com
… enable antibody evasion. Here we isolated an infectious Omicron virus in Belgium from a
traveller returning from Egypt. We examined its sensitivity to nine monoclonal antibodies that …

Antibody response to SARS-CoV-2 infection in humans: A systematic review

N Post, D Eddy, C Huntley, MCI Van Schalkwyk… - PloS one, 2020 - journals.plos.org
… detectable neutralising antibodies in response to SARS-CoV-2 … However, neutralising antibody
titres were low in a … 19) generated an antibody response capable of neutralising 42–99% …

Antibody neutralisation of emerging SARS-CoV-2 subvariants: EG. 5.1 and XBC. 1.6

Q Wang, Y Guo, RM Zhang, J Ho, H Mohri… - The Lancet Infectious …, 2023 - thelancet.com
… a small (1·7-fold) but significant increase in resistance to serum neutralisation compared
with XBB.1.16, which is known to have an antibody neutralisation profile similar to XBB.1.5. …

Neutralising antibody activity against SARS-CoV-2 VOCs B. 1.617. 2 and B. 1.351 by BNT162b2 vaccination

EC Wall, M Wu, R Harvey, G Kelly, S Warchal… - The Lancet, 2021 - thelancet.com
… clinical cohort, virus culture conditions, genetic sequencing, and neutralisation assays, and
… Using a high-throughput live-virus SARS-CoV-2 neutralisation assay (performance data are …