The immune complex: possible ways of regulating the antibody response

B Heyman - Immunology Today, 1990 - Elsevier
… F(ab') 2 fragments at high concentrations can suppress the antibody response, possibly by
… the suppressive effect of immune complexes on the response to Listeria monocytogenes in …

Antibody‐mediated regulation of the immune response

F Hjelm, F Carlsson, A Getahun… - Scandinavian journal of …, 2006 - Wiley Online Library
antibodies and external antigens form immune complexes in … antibody response can be
dependent on classical (antibody … or IgG3 is available to form complexes with the antigen. One …

Immune complexes can trigger specific, T cell-dependent, autoanti-IgG antibody production in mice.

DA Nemazee - The Journal of experimental medicine, 1985 - rupress.org
… The preference for IgG1 in the rheumatoid antibody response to immune complexes caused
by hyperimmunization appears to be due to three factors. First, the precursor frequency of B …

[PDF][PDF] Rheumatoid arthritis: the predictable effect of small immune complexes in which antibody is also antigen

JCW Edwards, G Cambridge - British journal of rheumatology, 1998 - academia.edu
Antibodies to IgG, or macrophages bearing the receptor FccRIIIa by immune complexes of
this type, with the producrheumatoid factors (RF), … A pathogenic role for immune complexes, …

Immune complex-mediated enhancement of secondary antibody responses

CL Goins, CP Chappell… - The Journal of …, 2010 - journals.aai.org
… We show that immune complexes formed in vivo between the Ag and pre-existing Abs from
the primary response activate these naive B cells, inducing them to respond with accelerated …

Enhancing antibody: a novel component of the immune response.

DA Nemazee, VL Sato - Proceedings of the National …, 1982 - National Acad Sciences
… bind complexes of anti-idiotypic IgG1 and idiotypic IgG1. This antibody had no specificity for
immune complexes formed between anti-idiotypic (Fab) fragments and idiotypic antibody or …

Immunization with immune complexes modulates the fine specificity of antibody responses to a flavivirus antigen

G Tsouchnikas, J Zlatkovic, J Jarmer, J Strauß… - Journal of …, 2015 - Am Soc Microbiol
… The antibody response to proteins may be modulated by the … antibodies and the formation
of immune complexes (ICs). Effects such as a general increase or decrease of the response as …

Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes

SB Halstead, S Mahalingam, MA Marovich… - The Lancet infectious …, 2010 - thelancet.com
… cross-linking of immune complexes with Fcγ receptors increases … antibody-dependent
enhancement (ADE) of infection. Intrinsic ADE is distinct from extrinsic ADE, whereby complexes

Antibody‐mediated modulation of immune responses

F Nimmerjahn, JV Ravetch - Immunological reviews, 2010 - Wiley Online Library
antibody-antigen complex [an immune complex (IC)] can negatively feed back on the humoral
immune response. … would help to ensure a long lasting antibody response. With respect to …

Immune complex‐mediated enhancement of antibody responses without induction of delayed‐type hypersensitivity

S Wernersson, S Kleinau… - Scandinavian journal of …, 2000 - Wiley Online Library
… Antigen-specific IgG and IgE antibodies are known to enhance the antibody response several
100-fold when given to mice together with protein antigens. The enhancing effect by IgE is …