Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers
As an extension for our earlier effort in the field of discovery of anticancer agents acting on
DNA and Topo II, eighteen quinoxaline derivatives were designed and synthesized. Such …
DNA and Topo II, eighteen quinoxaline derivatives were designed and synthesized. Such …
Synthesis and in vitro antitumor evaluation of betulin acid ester derivatives as novel apoptosis inducers
SJ Yang, MC Liu, HM Xiang, Q Zhao, W Xue… - European Journal of …, 2015 - Elsevier
… developing more potential anticancer drugs, in the present study nineteen BE derivatives
modified at C-3 and C-28 positions were designed and synthesized. The antitumor activities of …
modified at C-3 and C-28 positions were designed and synthesized. The antitumor activities of …
Development of pyridazine derivatives as potential EGFR inhibitors and apoptosis inducers: Design, synthesis, anticancer evaluation, and molecular modeling studies
… cell cycle progression, apoptotic induction and gene regulation … Moreover, the apoptotic
induction of UO-31 renal cancer … be considered as effective apoptosis modulators and promising …
induction of UO-31 renal cancer … be considered as effective apoptosis modulators and promising …
Design, synthesis, anticancer evaluation, and molecular modelling studies of novel tolmetin derivatives as potential VEGFR-2 inhibitors and apoptosis inducers
… of efficient anticancer agents that exhibited different enzymatic and cellular targets such
as apoptosis induction in different human cancer cell lines and inhibition of VEGFR-2. …
as apoptosis induction in different human cancer cell lines and inhibition of VEGFR-2. …
Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers
AMS El-Sharief, YA Ammar, A Belal… - Bioorganic …, 2019 - Elsevier
… apoptosis induction ability of the new promising anticancer … Measuring cell cycle arrest and
induction of apoptosis in … of cancer cells and induction of apoptosis was performed. Thus, we …
induction of apoptosis in … of cancer cells and induction of apoptosis was performed. Thus, we …
[HTML][HTML] Herbal medicine as inducers of apoptosis in cancer treatment
E Safarzadeh, SS Shotorbani… - Advanced …, 2014 - ncbi.nlm.nih.gov
… Induction of apoptosis is one of the most important markers of cytotoxic antitumor agents.
Some natural compounds including plants induce apoptotic pathways that are blocked in …
Some natural compounds including plants induce apoptotic pathways that are blocked in …
Discovery of 4-aryl-4H-chromenes as potent apoptosis inducers using a cell-and caspase-based Anti-cancer Screening Apoptosis Program (ASAP): SAR studies and …
SX Cai, J Drewe, W Kemnitzer - Anti-Cancer Agents in …, 2009 - ingentaconnect.com
… apoptosis inducers as potential anticancer agents [13] via developing a cell- and caspase-based
Anti-cancer Screening Apoptosis Program (ASAP) HTS assay for apoptosis inducers …
Anti-cancer Screening Apoptosis Program (ASAP) HTS assay for apoptosis inducers …
Biology and medicinal chemistry approaches towards various apoptosis inducers
VK Vyas, C Chintha… - Anti-Cancer Agents in …, 2013 - ingentaconnect.com
… of ASAP in filtering the compounds having apoptosis inducing activity [62]. … review
focuses on the literature pertaining to apoptosis inducers as potential vascular disrupting (anticancer) …
focuses on the literature pertaining to apoptosis inducers as potential vascular disrupting (anticancer) …
Synthesis, structure–activity relationships and preliminary antitumor evaluation of benzothiazole-2-thiol derivatives as novel apoptosis inducers
… To develop novel tumor growth inhibitors and apoptosis inducers as potential anticancer
agents, we designed and synthesized a series of benzothiazole-2-thiol derivatives, based on …
agents, we designed and synthesized a series of benzothiazole-2-thiol derivatives, based on …
Synthesis and in vitro evaluation of substituted quinolines as new apoptosis inducers and anticancer agents: Pharmacophore-based design
H Dayani, A Jha, M Ghate… - Letters in Drug Design & …, 2021 - ingentaconnect.com
… apoptosis inducers as anticancer agents, we performed ligand-based pharmacophore
modeling with known apoptosis inducers as anticancer … Known apoptosis inducers with diverse …
modeling with known apoptosis inducers as anticancer … Known apoptosis inducers with diverse …
相关搜索
- apoptosis inducers potential vegfr 2 inhibitors
- apoptosis inducers cell and caspase
- apoptosis inducers egfr inhibitors
- apoptosis inducers design synthesis
- apoptosis inducers preliminary antitumor evaluation
- efficacious anticancer agent potent apoptosis inducer
- apoptosis inducers anticancer agents
- biological evaluation potent apoptotic inducers
- apoptosis inducers potential anticancer activity
- synthesis and in vitro antitumor evaluation
- cytotoxicity and apoptosis induction
- apoptotic inducers chalcone moiety
- apoptotic inducers dna intercalators
- anticancer evaluation topoii inhibitors
- apoptosis inducers silico studies
- apoptosis inducers molecular modeling studies