… of drug with the DNA. In this review, we emphasize on cyclic voltammetric DNA binding …
been carried out in the last three decades for the investigation of their anticancer potentials. …

… drugs convert the topoisomerase molecule into a DNA damaging agent. This is a stoichiometric
relationship. Each anticancer drug molecule has the potential … to cause one DNA lesion. …

… specific DNA and … DNA G-quadruplexes in human gene promoters and telomeres, and the
opportunities presented for the development of G-quadruplex-targeted small-molecule drugs…

… However, no systematic work has so far been carried out to test its anti-cancer potential
against cervix cancer cells in vitro. Thus, in this study, we investigated whether ethanolic extract …

… The anticancer drugs adriamycin and daunomycin have each been crystallized with the DNA
sequence d(CGATCG) and the three-dimensional structures of the complexes solved at 1.7…

… DNA. From electrochemical data, the binding constant and binding ratio between DNA and
drug … that the mode of binding of GEM to DNA was through groove binding. A DPV method …

… targets for drug design, G-quadruplexes represent potentially important targets in drug
development. In this article, the structures of these unusual four-stranded DNA molecules, the …

… for the design of new anticancer drugs and chemical treatments of tumor … anticancer drugs
and DNA and establishing convenient methods to effectively choose specific anticancer drugs…

… In this review, we present results from recent structural studies of anticancer drugs acting on
DNA, particularly those involving covalent interactions. Some drugs are not discussed in this …

… In conclusion, the efficacy of this class of DNA-binding drugs, like that of anthracycline-based
anticancer drugs, is likely to involve tumour–host interactions as well as intrinsic cellular …