[HTML][HTML] Anticancer strategies based on the metabolic profile of tumor cells: therapeutic targeting of the Warburg effect

X Chen, L Li, Y Guan, J Yang, Y Cheng - Acta Pharmacologica Sinica, 2016 - nature.com
… of sufficient oxygen, a phenomenon termed the Warburg effect, which is the most outstanding
… agents may be effective anticancer strategies through weakening cell damage repair …

Revisiting the Warburg Effect: Diet‐Based Strategies for Cancer Prevention

Q Tran, H Lee, C Kim, G Kong, N Gong… - BioMed Research …, 2020 - Wiley Online Library
Anticancer strategies based on the Warburg effect have … We recently reviewed applications
of the Warburg effect to … strategies for cancer treatment based on the Warburg effect. …

Contemporary perspectives on the Warburg effect inhibition in cancer therapy

K Kozal, P Jóźwiak, A Krześlak - Cancer Control, 2021 - journals.sagepub.com
Anti-cancer strategies based on the Warburg effect involve not only the use of drug
compounds but also some dietary changes. Ketogenic diets that rely on cancer’s dependence on …

PPARs: interference with Warburg'effect and clinical anticancer trials

J Vamecq, JM Colet, JJ Vanden Eynde… - PPAR …, 2012 - Wiley Online Library
… The new anticancer strategies addressing tumoral stroma and metabolic coupling interfere
with and take place in the Warburg’s phenotype [51]. Like autophagy modulators, modulation …

From Warburg effect to Reverse Warburg effect; the new horizons of anti-cancer therapy

S Benny, R Mishra, MK Manojkumar, TP Aneesh - Medical hypotheses, 2020 - Elsevier
… Dr Otto Heinrich Warburg proposed this abnormal metabolic … the Warburg hypothesis termed
the Reverse Warburg effect … Reverse Warburg effect proposes a new anti-cancer treatment …

Metabolic targeting as an anticancer strategy: dawn of a new era?

JG Pan, TW Mak - Science's STKE, 2007 - science.org
… In the 1920s, Warburg noted that tumors exhibit increased rates of glycolysis even in the …
aerobic glycolysis or the "Warburg effect" (1). The Warburg effect is now considered a common …

The Warburg effect and its cancer therapeutic implications

Z Chen, W Lu, C Garcia-Prieto, P Huang - Journal of bioenergetics and …, 2007 - Springer
… have been shown to have promising anticancer activity in vitro and in vivo. … Warburg effect,
the underlying mechanisms, and its influence on the development of therapeutic strategies

The warburg effect: why and how do cancer cells activate glycolysis in the presence of oxygen?

M López-Lázaro - … Current Medicinal Chemistry-Anti-Cancer …, 2008 - ingentaconnect.com
… or Warburg effect). … a key anticancer strategy. Although some important knowledge has
been gained in the last few years on this growing field of research, the basis of the Warburg effect

The Warburg effect: evolving interpretations of an established concept

X Chen, Y Qian, S Wu - Free Radical Biology and Medicine, 2015 - Elsevier
… identify and formulate a more effective anticancer strategy by combining inhibition of glucose
… Besides potential side effects from ROS, targeting the Warburg effect may encounter some …

Exploring the mystery of tumor metabolism: Warburg effect and mitochondrial metabolism fighting side by side

Y Yu, Y Jiang, C Glandorff, M Sun - Cellular Signalling, 2024 - Elsevier
… Consequently, targeting mitochondrial metabolism emerges as a potent anticancer strategy
[… of potential therapeutic strategies, and propose various inhibitors for Warburg effect and …