Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to anticancer treatment
PO Berberat, Z Dambrauskas, A Gulbinas, T Giese… - Clinical cancer …, 2005 - AACR
… Heme oxygenase-1 (HO-1) is believed to represent a key … all known forms of anticancer
treatment, we have investigated … behavior and resistance to anticancer treatment were tested. …
treatment, we have investigated … behavior and resistance to anticancer treatment were tested. …
Antiapoptotic role of heme oxygenase (HO) and the potential of HO as a target in anticancer treatment
J Fang, T Akaike, H Maeda - Apoptosis, 2004 - Springer
Heme oxygenase-1 (HO-1) is an inducible enzyme that catalyzes oxidative degradation of
heme to form biliverdin, carbon monoxide (CO), and free iron. Biliverdin is subsequently …
heme to form biliverdin, carbon monoxide (CO), and free iron. Biliverdin is subsequently …
Heme oxygenase inhibition in cancers: Possible tools and targets
P Podkalicka, O Mucha, A Józkowicz, J Dulak… - Contemporary …, 2018 - termedia.pl
… treatment. Consequently, HO-1 can be proposed as a therapeutic target for anticancer treatment
in … In summary, HO-1 inhibition might be the valuable anticancer approach, however, the …
in … In summary, HO-1 inhibition might be the valuable anticancer approach, however, the …
Heme oxygenase-1 in tumor biology and therapy
H Was, J Dulak, A Jozkowicz - Current drug targets, 2010 - ingentaconnect.com
… Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to
anticancer treatment. Clin Cancer Res 2005; 11: 3790-8. [77] Marinissen MJ, Tanos T, Bolos M, …
anticancer treatment. Clin Cancer Res 2005; 11: 3790-8. [77] Marinissen MJ, Tanos T, Bolos M, …
Development and characterization of a new inhibitor of heme oxygenase activity for cancer treatment
O Mucha, P Podkalicka, M Mikulski, S Barwacz… - Archives of biochemistry …, 2019 - Elsevier
… between HMOX1 level and susceptibility to anti-cancer treatment, we have focused on …
prostate cancer were published showing both pro- and anti-cancer effect of HO-1 [27,28] we …
prostate cancer were published showing both pro- and anti-cancer effect of HO-1 [27,28] we …
Heme oxygenase-1 and its metabolites affect pancreatic tumor growth in vivo
P Nuhn, BM Künzli, R Hennig, T Mitkus… - Molecular cancer, 2009 - Springer
… to all current anticancer therapies. The cytoprotective enzyme heme oxygenase-1 (HO-1) is
… to play an important role in cancer resistance to anticancer treatment. The inhibition of HO-1 …
… to play an important role in cancer resistance to anticancer treatment. The inhibition of HO-1 …
A dual role of heme oxygenase-1 in cancer cells
SK Chiang, SE Chen, LC Chang - International journal of molecular …, 2018 - mdpi.com
Heme oxygenase (HO)-1 is known to metabolize heme into biliverdin/bilirubin, carbon
monoxide, and ferrous iron, and it has been suggested to demonstrate cytoprotective effects …
monoxide, and ferrous iron, and it has been suggested to demonstrate cytoprotective effects …
Heme oxygenase-1: emerging target of cancer therapy
LY Chau - Journal of biomedical science, 2015 - Springer
Heme oxygenase-1 (HO-1) is a rate-limiting enzyme catalyzing oxidative degradation of
cellular heme to liberate free iron, carbon monoxide (CO) and biliverdin in mammalian cells. In …
cellular heme to liberate free iron, carbon monoxide (CO) and biliverdin in mammalian cells. In …
Inhibition of heme oxygenase-1 enhances anti-cancer effects of arsenic trioxide on glioma cells
Y Liu, Y Liang, T Zheng, G Yang, X Zhang, Z Sun… - Journal of neuro …, 2011 - Springer
… In this study we showed that ATO induced cell damage and heme oxygenase-1 (HO-1)
expression in glioma cells via ROS generation. HO-1 inducer clearly protected from ATO-induced …
expression in glioma cells via ROS generation. HO-1 inducer clearly protected from ATO-induced …
Oncogenic potential of Nrf2 and its principal target protein heme oxygenase-1
HK Na, YJ Surh - Free Radical Biology and Medicine, 2014 - Elsevier
… stress-response proteins, especially heme oxygenase-1 (HO-1). … advantage and survival of
anticancer treatment. Therefore, Nrf2 … /resistance to anticancer treatments, and metastasis or …
anticancer treatment. Therefore, Nrf2 … /resistance to anticancer treatments, and metastasis or …