A translational rodent assay of affective biases in depression and antidepressant therapy
SA Stuart, P Butler, MR Munafo, DJ Nutt… - …, 2013 - nature.com
… induced in our test also mirror the antidepressant and pro-… Our results suggest that cognitive
affective biases could contribute to … mechanism contributes to antidepressant drug efficacy. …
affective biases could contribute to … mechanism contributes to antidepressant drug efficacy. …
Effect of acute antidepressant administration on negative affective bias in depressed patients
CJ Harmer D Phil, U O'Sullivan… - American Journal of …, 2009 - Am Psychiatric Assoc
… of antidepressant treatment are not usually explored in a psychological framework, and
reductions of biases toward aversive information following antidepressant … that antidepressants …
reductions of biases toward aversive information following antidepressant … that antidepressants …
Affective biases in humans and animals
ESJ Robinson, JP Roiser - Translational neuropsychopharmacology, 2016 - Springer
… These affective biases are sensitive to antidepressant treatments … affective biases has also
facilitated back-translation to animals and the development of assays to study affective biases …
facilitated back-translation to animals and the development of assays to study affective biases …
Further validation of the affective bias test for predicting antidepressant and pro-depressant risk: effects of pharmacological and social manipulations in male and …
… Affective biases are hypothesised to contribute to the … that affective biases, associated with
learning and memory, are observed following acute treatments with a range of antidepressant …
learning and memory, are observed following acute treatments with a range of antidepressant …
Rapid-acting antidepressant drugs modulate affective bias in rats
JK Hinchcliffe, SA Stuart, CM Wood, J Bartlett… - Science translational …, 2024 - science.org
… to quantify the affective bias generated. … affective bias in the affective bias test. Low, but not
high, doses of ketamine and psilocybin reversed the valence of the negative affective bias 24 …
high, doses of ketamine and psilocybin reversed the valence of the negative affective bias 24 …
Emotional processing and antidepressant action
CJ Harmer - Behavioral neurobiology of depression and its …, 2013 - Springer
… This chapter will review the role of psychological emotional biases in depression and the
evidence that antidepressant treatments may work via early correction of emotional biases. …
evidence that antidepressant treatments may work via early correction of emotional biases. …
The cognitive neuropsychological model of antidepressant response
AEL Walsh, CJ Harmer - Current Opinion in Psychology, 2015 - Elsevier
… Antidepressants affect negative affective bias in depression … Changes in negative affective
bias with antidepressants … The requirement for changes in negative affective biases and …
bias with antidepressants … The requirement for changes in negative affective biases and …
Why do antidepressants take so long to work? A cognitive neuropsychological model of antidepressant drug action
… role and importance of negative affective biases in depression. Here, we review the evidence
for the cognitive neuropsychological theory of antidepressant drug action and identify the …
for the cognitive neuropsychological theory of antidepressant drug action and identify the …
Serotonin and emotional processing: does it help explain antidepressant drug action?
CJ Harmer - Neuropharmacology, 2008 - Elsevier
… It would therefore be predicted that changes in bias seen with antidepressant administration
would protect against mood collapse following an aversive or stressful challenge. Further it …
would protect against mood collapse following an aversive or stressful challenge. Further it …
[HTML][HTML] Predicting treatment response to antidepressant medication using early changes in emotional processing
M Browning, J Kingslake, CT Dourish… - European …, 2019 - Elsevier
… bias and subjective symptoms before starting antidepressant … The face based measure of
emotional bias provided good … early measure of antidepressant efficacy for individual patients…
emotional bias provided good … early measure of antidepressant efficacy for individual patients…
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