Survival and course of lung function in the presence or absence of antifibrotic treatment in patients with idiopathic pulmonary fibrosis: long-term results of the …

J Behr, A Prasse, H Wirtz, D Koschel… - European …, 2020 - Eur Respiratory Soc
… Effective treatments are still limited. The antifibrotic treatments pirfenidone and nintedanib
have been shown to slow disease progression as measured by annual rate of decline in …

Real-world study analysing progression and survival of patients with idiopathic pulmonary fibrosis with preserved lung function on antifibrotic treatment

S Noor, S Nawaz, N Chaudhuri - Advances in therapy, 2021 - Springer
… The UK restricts antifibrotic treatment to patients with a forced … The hypothesis of this study
is that antifibrotic treatment (… outcomes with regards to disease progression and survival. …

Efficacy of early antifibrotic treatment for idiopathic pulmonary fibrosis

K Sugino, H Ono, N Watanabe, M Ando… - BMC Pulmonary …, 2021 - Springer
… We compared survival and disease progression between patients with IPF with Japanese
Respiratory Society (JRS) disease severity system stage I with and without oxygen …

When to start and when to stop antifibrotic therapies

SE Torrisi, M Pavone, A Vancheri… - European Respiratory …, 2017 - Eur Respiratory Soc
… of antifibrotic drugs in reducing its progression and improving survival, that there should be
less doubt about treating … time of diagnosis, and antifibrotic treatment should be stopped only …

Improved survival of IPF patients treated with antifibrotic drugs compared with untreated patients

MGJP Platenburg, CHM van Moorsel, IA Wiertz… - Lung, 2023 - Springer
… a survival difference between patients treated with corticosteroids for ≥ 6 months and patients
who were not or treated … AF drugs are associated with a survival benefit in IPF and cannot …

[HTML][HTML] Effect of antifibrotic therapy on survival in patients with idiopathic pulmonary fibrosis

JA de Andrade, ML Neely, AS Hellkamp, DA Culver… - Clinical Therapeutics, 2023 - Elsevier
… for antifibrotic drugs extending survival in patients with IPF by slowing disease progression,
… in mortality can be attributed to the use of antifibrotic therapy. Our findings are supported by …

Anti-fibrotic treatments: a review of clinical evidence

M Allinovi, L De Chiara, ML Angelotti, F Becherucci… - Matrix Biology, 2018 - Elsevier
… of renal fibrogenesis and the emerging anti-fibrotic drugs that have shown encouraging …
options and future directions in which anti-fibrotic treatments may be coupled with drugs that …

Prognosis of idiopathic pulmonary fibrosis without anti-fibrotic therapy: a systematic review

YH Khor, Y Ng, H Barnes, NSL Goh… - European …, 2020 - Eur Respiratory Soc
… patients with IPF who either were untreated or had not received effective treatments. Without
anti-fibrotic therapy, the overall survival rates for this condition are poor. Although limited by …

Antifibrotic therapy to normalize the tumor microenvironment

A Hauge, EK Rofstad - Journal of translational medicine, 2020 - Springer
… with PEGPH20 in addition to chemotherapy experienced increased progression-free
survival as compared to patients treated with chemotherapy alone [64]. Further, the difference …

Antifibrotic therapy for idiopathic pulmonary fibrosis: time to treat

TM Maher, ME Strek - Respiratory research, 2019 - Springer
antifibrotic therapies have been approved for the treatment of … studies, suggest that
antifibrotic therapies improve life … potential side-effects of antifibrotic drugs. There remains a …