Regulation of the immune response by antigen

RM Zinkernagel, H Hengartner - Science, 2001 - science.org
antigen that determine whether an immune response can be accurately measured against
model antigens … We suggest that antigen structure, localization, dose, and time during which …

Cell selection by antigen in the immune response

GW Siskind, B Benacerraf - Advances in immunology, 1969 - Elsevier
immune response, to select those cells of highest antigen-binding affinity from a proliferating
immune … view of the immune response, in which availability of antigen serves as the crucial …

Role of O-antigen variation in the immune response

P Reeves - Trends in microbiology, 1995 - cell.com
… The interactions between 0 antigen and the immune system are central to determining
the … O-antigen capsule, in addition to 0 antigen forming part of the LPS. The role of the O-antigen

Role of natural and immune IgM antibodies in immune responses

M Boes - Molecular immunology, 2000 - Elsevier
… elicit a humoral immune response that is characterized by an early rise of antigen-specific …
, and the ensuing rise in antigen-specific IgG, IgA and IgE antibodies. The sera of humans …

Antigen localisation regulates immune responses in a dose‐and time‐dependent fashion: a geographical view of immune reactivity

RM Zinkernagel, S Ehl, P Aichele, S Oehen… - Immunological …, 1997 - Wiley Online Library
… The critical role of antigen in regulating immune responses al.so bas … antigen, dependent
upon locahsation, dose and time, seems to be the simplest regulator of immune responses

Natural antibodies and the immune response

SV Boyden - Advances in immunology, 1966 - Elsevier
… Although a great deal has been written about the antibodiesantibodies might play an
important role in immune responses, It … What is the first thing that happens to the antigen molecule …

Immune responses to tumour antigens: implications for antigen specific immunotherapy of cancer

D Jäger, E Jäger, A Knuth - Journal of clinical pathology, 2001 - jcp.bmj.com
… CTL responses in vivo. Immunological and clinical parameters for the assessment of antigen
specific immune responses … , and tumour regression responses. Specific DTH and CTL …

Antigen recognition and the immune response: humoral and cellular immune responses to small mono-and bifunctional antigen molecules

SS Alkan, EB Williams, DE Nitecki… - The Journal of …, 1972 - rupress.org
… The names and structures of the compounds used as antigens in this investigation are shown
in Table I. A detailed description of their preparation and characterization will be published …

Enhancing immune responses by targeting antigen to DC

I Caminschi, MH Lahoud… - European journal of …, 2009 - Wiley Online Library
… up” the mAb carrying the antigen cargo. Thus, the efficiency of … in targeting antigens and
enhancing immune responses 19 may … antigen by other cell types may directly affect the immune

The effect of genetic origin, source of antigen, and dose of antigen on the immune response of cockerels

AJ Van der Zijpp - Poultry Science, 1983 - Elsevier
… SRBC) was chosen so that an immune response might be expected. In a previous study it
was shown that a very low dose (.0005 ml) does not invoke a response and a very high dose (…