Evolution in miniature: selection, survival and distribution of antigen reactive cells in the germinal centre

DM Tarlinton - Immunology and cell biology, 2008 - Wiley Online Library
… B cells, which may also bind antigen. The simplest way of achieving this is to impose the
criterion that antigen-reactive cells will … Isotype switching is a post-activation feature of the B-cell

Specific Inactivation of Antigen-reactive Cells with 125I-Labelled Antigen

GL Ada, P Byrt - Nature, 1969 - nature.com
… of these cells to react with antigen was immunologically … the reactive cells were ( 1)
cells present because of a prior experience of the animal with a related antigen, (2) antigen-reactive

The thymus and the precursors of antigen reactive cells

J Miller, GF Mitchell - Nature, 1967 - nature.com
… We report here the results of a time course study on the appearance of antigen-reactive
cells in normal and thymectomized irradiated mice injected with bone marrow cells, thymus …

Generation of human monoclonal antibodies reactive with cellular antigens.

RJ Cote, DM Morrissey, AN Houghton… - Proceedings of the …, 1983 - National Acad Sciences
… The production of antibody reactive against cellsurface or intracellular antigens was tested …
target cells (Table 4); <1% of the cultures showed detectable antibody to cell-surface antigens

Antigen-reactive cells in normal, immunized, and tolerant mice

WD Armstrong, E Diener, GR Shellam - The Journal of Experimental …, 1969 - rupress.org
… x The following abbreviations are used in this paper: ARC, antigen-reactive cell; POL,
polymer antigen of S. adelaide flagellin; AFC, antibody-forming cell; TDL, thoracic duct …

Antigen‐specific and cross‐reactive T cells in protection and disease

N Jiang, M Malone, S Chizari - Immunological reviews, 2023 - Wiley Online Library
… of these antigen‐driven T‐cell responses, with a particular focus on CD8+ T cells, using …
throughput profiling of antigen‐specific and cross‐reactive T‐cell responses experimentally, …

Peripheral deletion of antigen-reactive T cells in oral tolerance

Y Chen, J Inobe, R Marks, P Gonnella, VK Kuchroo… - Nature, 1995 - nature.com
… the dose of antigen fed". Here we report that oral antigen can delete antigen-reactive T cells
in Peyer's patches, in mice transgenic for the ovalbumin-specific T-cell receptor genes. The …

Quantification of antigenreactive cells among human T lymphocytes

MHJ Van Oers, J Pinkster… - European journal of …, 1978 - Wiley Online Library
… We have studied the frequency of memory T cells for the bacterial antigens tuberculin PPD …
-reactive T cells. In 11 different donors, the observed frequencies of the antigen-reactive T cell

The regulation of self-reactive B cells

RJ Cornall, CC Goodnow, JG Cyster - Current opinion in immunology, 1995 - Elsevier
… membrane-bound antigen can cause the deletion of self-reactive cells ensures that there is
… -bound antigens, particularly those likely to be encountered on haemopoietic cells and blood-…

Major histocompatibility complex-restricted antigen presentation to antigen-reactive T cells by B lymphocyte tumor cells.

DJ McKean, AJ Infante, A Nilson, M Kimoto… - The Journal of …, 1981 - rupress.org
… present the antigen to the antigen-reactive T cells. To … cells, we treated the antigen-reactive
T cells with anti-Ia and complement before testing with spleen or tumor cells in the antigen-…