Antigen receptor structure and signaling

F Han, Y Chen, Y Zhu, Z Huang - Advances in Immunology, 2023 - Elsevier
structural resolution, based on antigen recognition receptors … , elicit effective antigen-specific
neutralizing antibodies and … In conclusion, the study of antigen receptors structure and …

[PDF][PDF] T cell antigen receptor: structure, assembly and function

AM Weissman, JS Bonifacino, RD Klausner… - Year …, 1989 - researchgate.net
Structural analysis of the extracellular regions shows a potential evolutionary relationship to
… quantities relative to the other receptor components as analyzed by immunoblotting and a …

Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR

MC Bewley, K Springer, YB Zhang, P Freimuth… - Science, 1999 - science.org
… The crystal structure of the adenovirus fiber knob domain in complex with domain I of its
human cellular receptor, coxsackie and adenovirus receptor (CAR), is presented here. Surface-…

T cell antigen receptor recognition of antigen-presenting molecules

J Rossjohn, S Gras, JJ Miles, SJ Turner… - Annual review of …, 2015 - annualreviews.org
… In contrast, structural analysis of a different TCR (clone ELS4) that bound to an HLA-B*35:01-11-mer
complex indicated that this peptide was more flexible and was flattened upon TCR …

The evolutionary and structural 'logic'of antigen receptor diversity

MM Davis - Seminars in immunology, 2004 - Elsevier
antigen receptor gene evolution. At this point, what is needed in the future is more structural
work on primary antibodies… the postulated differences in antigen binding to the different parts …

Identification of antigen receptor-associated structures on murine T cells

JP Allison, LL Lanier - Nature, 1985 - nature.com
… with the heterodimer structure implicated as the T-cell antigen receptor. Further structural and
… Leu 4/T3-like structure await production of an antibody against this antigen, which will be …

Structure of a human γδ T-cell antigen receptor

TJ Allison, CC Winter, JJ Fournié, M Bonneville… - Nature, 2001 - nature.com
antigen receptors composed of γ and δ polypeptide chains (γδTCRs) can directly recognize
antigens … , unlike αβTCRs, which recognize antigens bound to major histocompatibility …

Genetic analysis of B cell antigen receptor signaling

T Kurosaki - Annual review of immunology, 1999 - annualreviews.org
… Crystal structure analyses of Src-family PTKs reveal that the SH3 domainrecognizes the
linker region between the SH2 domain and the kinase domain(65,66). Thus, two interactions, …

Comparative analysis of the CDR loops of antigen receptors

WK Wong, J Leem, CM Deane - Frontiers in immunology, 2019 - frontiersin.org
… If we consider structures with a difference of <1Åin backbone RMSD as similar (… antibodies),
this analysis illustrates that the majority of the sequence-identical structures are structurally

Structure and diversity of the T cell antigen receptor beta-chain in a teleost fish.

S Partula, A De Guerra, JS Fellah… - Journal of immunology …, 1995 - journals.aai.org
… of several Cp isotypes, although all clones analyzed in the present study had identical CP
… Members of the Vp2 family were used in 13 clones among 21 analyzed clones from our …