A new subunit of the human T-cell antigen receptor complex

AM Weissman, LE Samelson, RD Klausner - Nature, 1986 - nature.com
… recognition of antigen by this receptor leads to … structure of the human T-cell antigen
receptor. On human T cells, clonally determined, disulphide-linked ar and (8 chains of the receptor

Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor

VA Streltsov, JN Varghese… - Proceedings of the …, 2004 - National Acad Sciences
… Sequence alignments show IgNAR antibody variability confined to the CDR1 and CDR3,
and this result is confirmed by our structural analysis. CDR1 is the minor loop component, …

The T cell antigen receptor.

MK Collins, MJ Owen - Biochemical Journal, 1985 - ncbi.nlm.nih.gov
… In this case the surface antigen T3 provides a further useful marker. Because of its co-ordinate
expression with the antigen receptor (see protein structure) it can be regarded as a …

Structural analysis of the CD5 antigen: Expression, disulphide bond analysis and physical characterisation of CD5 scavenger receptor superfamily domain 1

MSB McALISTER, MH Brown, AC Willis… - European journal of …, 1998 - Wiley Online Library
analysis to gain an overview of the structure of the extracellular portion of intact CD5.
Carbohydrate analysis … Electron microscopy and carbohydrate analysis together suggest that the …

Structural design and molecular evolution of a cytokine receptor superfamily.

JF Bazan - Proceedings of the National Academy of …, 1990 - National Acad Sciences
… from the receptor supergroup reveal clear evolutionary links to fibronectin type m structures,
-… Predictive structural analysis of the shared receptor and fibronectin domains locates seven f-…

How much can a T‐cell antigen receptor adapt to structurally distinct antigenic peptides?

C Mazza, N Auphan‐Anezin, C Gregoire… - The EMBO …, 2007 - embopress.org
… Binding degeneracy is thought to constitute a fundamental property of the T‐cell antigen
receptor (TCR), yet its structural basis is poorly understood. We determined the crystal structure

Structural analysis of histo-blood group antigen binding specificity in a norovirus GII. 4 epidemic variant: implications for epochal evolution

S Shanker, JM Choi, B Sankaran, RL Atmar… - Journal of …, 2011 - Am Soc Microbiol
… domain structure and contribute to epochal evolution, we determined the P domain structure
… and compared it with the previously determined structure of a 1996 variant. We show that …

T-cell antigen receptor genes and T-cell recognition

MM Davis, PJ Bjorkman - Nature, 1988 - nature.com
… We also attempt to rationalize some of these observations with respect to structural
aspects of antigen-MHC recognition and to the evolution of the antigen receptor (TCR and …

A structural model of a seven-transmembrane helix receptor: the Duffy antigen/receptor for chemokine (DARC)

AG De Brevern, H Wong, C Tournamille, Y Colin… - … et Biophysica Acta (BBA …, 2005 - Elsevier
… In this study, we elaborate and analyze structural models of the DARC. The construction of
… proteins with known structures. Threading, ab initio, secondary structure and Protein Blocks …

Monomeric and oligomeric complexes of the B cell antigen receptor

WWA Schamel, M Reth - Immunity, 2000 - cell.com
… The current structural model of the B cell antigen receptor (BCR) describes it as a …
analysis after limited detergent lysis provides further evidence for an oligomeric BCR structure