The role of anti-malarial drugs in eliminating malaria

NJ White - Malaria journal, 2008 - Springer
… detectable gametocytaemia can transmit these malaria infections. Because the majority of
anti-malarial drugs has less effect on overall transmission compared with falciparum malaria

The mechanisms of resistance to antimalarial drugs in Plasmodium falciparum

J Le Bras, R Durand - Fundamental & clinical pharmacology, 2003 - Wiley Online Library
… a high level of malaria transmission, and falciparum chloroquine-resistant prevalence
seems to stabilize at the same level as chloroquine-sensitive malaria. Nevertheless, resistance …

Drugs in development for malaria

EA Ashley, AP Phyo - Drugs, 2018 - Springer
… The last two decades have seen a surge in antimalarial drugfalciparum to the artemisinin
derivatives, piperaquine and mefloquine in Southeast Asia means new antimalarials are …

Population biology and antimalarial resistance: The transmission of antimalarial drug resistance in Plasmodium falciparum

KI Barnes, NJ White - Acta tropica, 2005 - Elsevier
falciparum malaria, a wave of gametocytes generally appears in the peripheral blood
after 6–10 days, even when treated. Gametocytes display a diurnal subperiodic pattern, with …

Defining the timing of action of antimalarial drugs against Plasmodium falciparum

DW Wilson, C Langer, CD Goodman… - Antimicrobial agents …, 2013 - Am Soc Microbiol
antimalarials for treatment of clinical Plasmodium falciparum malaria fall into two broad drug
falciparum malaria are focused either on the food vacuole of ring-stage and trophozoites of …

New antimalarial drugs

J Wiesner, R Ortmann, H Jomaa… - Angewandte Chemie …, 2003 - Wiley Online Library
… of antimalarial drugs been renewed. New data available from the recently sequenced genome
of the malaria parasite Plasmodium falciparum and the application of methods of modern …

Effect of Antimalarial Drugs on Plasmodium falciparum Gametocytes

CL Peatey, TS Skinner-Adams… - The Journal of …, 2009 - academic.oup.com
… of malaria parasites to antimalarial drugs. An advantage of in vitro testing is the ability to
measure the susceptibility of Plasmodium falciparum parasites to antimalarial drugs in the …

[PDF][PDF] Assessment of therapeutic efficacy of antimalarial drugs: for uncomplicated falciparum malaria in areas with intense transmission

World Health Organization - 1996 - apps.who.int
… of antimalarial drugs against clinically manifest infections with Plasmodium falciparum in …
in WHO document WHO/MAL/94.1070, Antimalarial Drug Policies. In addition it is based on …

Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic

B Blasco, D Leroy, DA Fidock - Nature medicine, 2017 - nature.com
… The global adoption of artemisinin-based combination therapies (ACTs) in the early 2000s
heralded a new era in effectively treating drug-resistant Plasmodium falciparum malaria. …

Anti-malarial drugs: how effective are they against Plasmodium falciparum gametocytes?

CL Peatey, D Leroy, DL Gardiner, KR Trenholme - Malaria Journal, 2012 - Springer
… Late-stage gametocytes (stages IV-V) are more resistant to anti-malarial drugs and … the
only licensed anti-malarial drug that is effective against late stage P. falciparum gametocytes but …