Natural antimicrobial peptides from bacteria: characteristics and potential applications to fight against antibiotic resistance

M Hassan, M Kjos, IF Nes, DB Diep… - Journal of applied …, 2012 - academic.oup.com
… In this review, we discuss the emerging antibiotic resistance and … antimicrobial peptides
from bacteria (bacteriocins) as a means to fight the serious problem of antibiotic resistance

Antimicrobial peptides: the Achilles' heel of antibiotic resistance?

A Lewies, LH Du Plessis, JF Wentzel - Probiotics and antimicrobial …, 2019 - Springer
… potential of antimicrobial peptides (AMPs) to combat the threat of antimicrobial resistance. …
This report projects that by 2050 antibiotic resistance could potentially lead to 10 million …

The development of antimicrobial peptides as an approach to prevention of antibiotic resistance

MM Moghaddam, H Aghamollaei… - … and Research in …, 2015 - journals.lww.com
… pathogens becoming resistant to these antibiotics. … that antimicrobial peptides (AMPs) and
proteins are important members of the host defense system in eukaryotes. These peptides are …

[HTML][HTML] Insect antimicrobial peptides: potential weapons to counteract the antibiotic resistance

MD Manniello, A Moretta, R Salvia, C Scieuzo… - Cellular and Molecular …, 2021 - Springer
resistance of the bacterial community to the host immune system by decreasing efficacy of
antibodies and antimicrobial peptides (… of antibiotics, thus, reducing their antimicrobial efficacy. …

Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides

V Lázár, A Martins, R Spohn, L Daruka, G Grézal… - Nature …, 2018 - nature.com
… set of 24 antimicrobial peptides of diverse … antimicrobial peptides. Analysis of the mutational
and transcriptome profiles of the antibiotic-resistant strains revealed that antibiotic-resistance

[HTML][HTML] Antibiotic development challenges: the various mechanisms of action of antimicrobial peptides and of bacterial resistance

F Guilhelmelli, N Vilela, P Albuquerque… - Frontiers in …, 2013 - frontiersin.org
Antimicrobial peptides (AMPs) are natural antibiotics produced by various organisms such
as mammals, arthropods, plants, and bacteria. In addition to antimicrobial activity, AMPs can …

[HTML][HTML] Application of antimicrobial peptides of the innate immune system in combination with conventional antibiotics—a novel way to combat antibiotic resistance?

MS Zharkova, DS Orlov, OY Golubeva… - Frontiers in cellular …, 2019 - frontiersin.org
… application of antimicrobial peptides with antibiotics or other antimicrobials is a …
antibiotic-resistant bacteria by usage of AMP-based therapeutics. Revealing the conventional …

The value of antimicrobial peptides in the age of resistance

M Magana, M Pushpanathan, AL Santos… - The lancet infectious …, 2020 - thelancet.com
… development of antimicrobial peptides as … antimicrobial peptides against multidrug-resistant
pathogens, highlights advances in the deployment of novel promising antimicrobial peptides

Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice

R Mourtada, HD Herce, DJ Yin, JA Moroco… - Nature …, 2019 - nature.com
The clinical translation of cationic α-helical antimicrobial peptides (AMPs) has been
hindered by structural instability, proteolytic degradation and in vivo toxicity from nonspecific …

Proline-rich antimicrobial peptides: potential therapeutics against antibiotic-resistant bacteria

W Li, J Tailhades, NM O'Brien-Simpson, F Separovic… - Amino acids, 2014 - Springer
Antimicrobial peptides, part of native host defense, have emerged as … antibiotic alternatives.
Among the different classes of antimicrobial peptides, proline-rich antimicrobial peptides, …