Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
… that can be employed to improve AMP activity to combat global antimicrobial resistance. … ,
and rational design/improvement of AMPs; (ii) CAMPSign feature searches for peptide patterns …

Systematic analysis of global features and model building for recognition of antimicrobial peptides

EG Randou, D Veltri, A Shehu - 2013 IEEE 3rd International …, 2013 - ieeexplore.ieee.org
… that uses these features in isolation or combination to predict whether a peptide is AMP or
not… , we focus here on eight global (whole-peptide) features shown recently to allow SVM- and …

A review on antimicrobial peptides databases and the computational tools

S Ramazi, N Mohammadi, A Allahverdi, E Khalili… - Database, 2022 - academic.oup.com
Antimicrobial Peptides (AMPs) have been considered as … been raised as a global problem.
The AMPs are a group of natural … peptide features was then extracted and to filter this feature

The value of antimicrobial peptides in the age of resistance

M Magana, M Pushpanathan, AL Santos… - The lancet infectious …, 2020 - thelancet.com
… and global expansion of antimicrobialantimicrobial peptides against multidrug-resistant
pathogens, highlights advances in the deployment of novel promising antimicrobial peptides, …

Antimicrobial peptides: features, applications and the potential use against covid-19

DM Mabrouk - Molecular Biology Reports, 2022 - Springer
… This review provides a brief history of AMPs and their features, including classification,
evolution, sources and mechanisms of action, biosynthesis pathway, and identification techniques…

Characterization and identification of antimicrobial peptides with different functional activities

CR Chung, TR Kuo, LC Wu, TY Lee… - Briefings in …, 2020 - academic.oup.com
… —an issue that has developed into a global crisis [1]. Antimicrobial peptides (AMPs) are a
… Most of the top 10 CTDD features in our study were also among the 23 features used in [6]. …

[HTML][HTML] Structural features of helical antimicrobial peptides: their potential to modulate activity on model membranes and biological cells

M Dathe, T Wieprecht - Biochimica et Biophysica Acta (BBA) …, 1999 - Elsevier
… The activity of these peptides is thought to be determined by global structural parameters
rather than by the specific amino acid sequence. This review is concerned with the influence of …

Designing antimicrobial peptides: form follows function

CD Fjell, JA Hiss, REW Hancock… - Nature reviews Drug …, 2012 - nature.com
… This probably requires nascent or induced (via peptide–membrane interaction) structural
features of … the global three-dimensional conformation of the peptide 88 . Using high-throughput …

Antimicrobial peptides: Structure, mechanism, and modification

N Chen, C Jiang - European Journal of Medicinal Chemistry, 2023 - Elsevier
… The WHO's report noted that 700,000 people die globally from drug-resistant … feature of
α-helical peptides is that the C-terminus is mostly amidated, so it has stronger antimicrobial

The vast structural diversity of antimicrobial peptides

J Koehbach, DJ Craik - Trends in pharmacological sciences, 2019 - cell.com
Antimicrobial peptides (AMPs) occur in all kingdoms of life and are integral to host defense.
They … immediate and global action the world is headed for a dangerous post-antibiotic era [ …