What can machine learning do for antimicrobial peptides, and what can antimicrobial peptides do for machine learning?

EY Lee, MW Lee, BM Fulan, AL Ferguson… - Interface …, 2017 - royalsocietypublishing.org
… applications of machine learning to … machine learning on AMPs can be used to identify
essential physico-chemical determinants of AMP functionality, and identify and design peptide

Combining genetic algorithm with machine learning strategies for designing potent antimicrobial peptides

K Boone, C Wisdom, K Camarda, P Spencer… - BMC …, 2021 - Springer
machine learning to guide the sequence selection process. Our results demonstrate that
antimicrobial peptide … The proposed approach could be extended to peptide design with other …

Using evolutionary algorithms and machine learning to explore sequence space for the discovery of antimicrobial peptides

M Yoshida, T Hinkley, S Tsuda, YM Abul-Haija… - Chem, 2018 - cell.com
… We demonstrate this by optimizing the efficacy of antimicrobial peptides (AMPs). In particular…
, machine learning, and in vitro evaluation to improve the antimicrobial activity of peptides

Machine learning prediction of antimicrobial peptides

G Wang, II Vaisman, ML van Hoek - … peptide science: Methods and …, 2022 - Springer
peptides. Finally, we discuss advances, limitations, and future directions of machine-learning
predictions of antimicrobial peptides. … of such predictions beyond antimicrobial activity to …

Comprehensive assessment of machine learning-based methods for predicting antimicrobial peptides

J Xu, F Li, A Leier, D Xiang, HH Shen… - Briefings in …, 2021 - academic.oup.com
… original sequences as the inputs are seldomly used for training machine learning methods.
… In this article, we first provide a comprehensive survey on current machine learning-based …

Machine learning designs non-hemolytic antimicrobial peptides

A Capecchi, X Cai, H Personne, T Köhler… - Chemical …, 2021 - pubs.rsc.org
Machine learning (ML) consists of the recognition of patterns from training data and offers …
In the area of peptide drugs, ML is mostly being tested to design antimicrobial peptides (AMPs)…

AMPGAN v2: machine learning-guided design of antimicrobial peptides

CM Van Oort, JB Ferrell, JM Remington… - Journal of chemical …, 2021 - ACS Publications
Machine learning has aided in the discovery … , antimicrobial activity), train a machine learning
model to predict that property using relatively easily obtained features (eg, primary peptide

Recent progress in the discovery and design of antimicrobial peptides using traditional machine learning and deep learning

J Yan, J Cai, B Zhang, Y Wang, DF Wong, SWI Siu - Antibiotics, 2022 - mdpi.com
… cataloged in the Antimicrobial Peptide Database (APD) [5]… antimicrobial potential of new
sequences. In this paper, traditional ML refers to all ML methods such as support vector machine

Machine learning-enabled predictive modeling to precisely identify the antimicrobial peptides

MA Wani, P Garg, KK Roy - Medical & Biological Engineering & Computing, 2021 - Springer
machine learning tools to develop in silico models as AMP predictors. In this paper, we have
explored several machine learning … (k-NN) [1], Support Vector Machine (SVM) [6], Decision …

An advanced approach to identify antimicrobial peptides and their function types for penaeus through machine learning strategies

Y Lin, Y Cai, J Liu, C Lin, X Liu - BMC bioinformatics, 2019 - Springer
… In this study, we made an attempt to develop an advanced machine learning based computational
approach, MAMPs-Pred, for identification of AMPs and its function types. Initially, SVM-…