Target-AMP: Computational prediction of antimicrobial peptides by coupling sequential information with evolutionary profile

A Jan, M Hayat, M Wedyan, R Alturki… - Computers in Biology …, 2022 - Elsevier
… The training dataset consisted of 3175 peptide sequences, of which 770 are antimicrobial
peptides and 2405 are non-antimicrobial peptides. On the other hand, 1840 peptides in the …

Detecting antimicrobial peptides by exploring the mutual information of their sequences

V Tripathi, P Tripathi - Journal of Biomolecular Structure and …, 2020 - Taylor & Francis
… The results obtained in this study indicate that the mutual information of a peptide sequence
can be an efficient feature tool for predicting the AMPs. In particular, the MIV method takes …

Prediction of antimicrobial peptides based on sequence alignment and feature selection methods

P Wang, L Hu, G Liu, N Jiang, X Chen, J Xu, W Zheng… - PloS one, 2011 - journals.plos.org
… are rich in antimicrobial peptides (Figure … antimicrobial and non-antimicrobial peptides. Our
results further confirm that amino acid composition is important for identify whether a peptide

[PDF][PDF] Identification of Antimicrobial Peptides Using Chou's 5 Step Rule.

SJ Malebary, YD Khan - Computers, Materials & Continua, 2021 - cdn.techscience.cn
… While doing this frequency matrix completely disregards the protein sequence information.
Accumulative absolute position incidence vector (AAPIV) describes the absolute position of …

CAMP: a useful resource for research on antimicrobial peptides

S Thomas, S Karnik, RS Barai… - Nucleic acids …, 2010 - academic.oup.com
… understanding on antimicrobial peptides. It is manually curated and currently holds 3782
antimicrobial sequences… Sequence changes may not always render the peptide completely non-…

Sequence requirements and an optimization strategy for short antimicrobial peptides

K Hilpert, MR Elliott, R Volkmer-Engert, P Henklein… - Chemistry & biology, 2006 - cell.com
… In this paper, we have applied this newly developed method to increase understanding
of the primary sequence requirements for short antimicrobial peptides (12 amino acids) in …

The value of antimicrobial peptides in the age of resistance

M Magana, M Pushpanathan, AL Santos… - The lancet infectious …, 2020 - thelancet.com
antimicrobial peptides as novel therapeutics. This Review identifies the benefits, challenges,
and opportunities of using antimicrobial peptides … of novel promising antimicrobial peptides, …

AmPEP: Sequence-based prediction of antimicrobial peptides using distribution patterns of amino acid properties and random forest

P Bhadra, J Yan, J Li, S Fong, SWI Siu - Scientific reports, 2018 - nature.com
Antimicrobial peptides (AMPs) are promising candidates in the fight against multidrug-…
patterns of amino acid properties along the sequence. Using our collection of large and diverse …

Characterization and identification of antimicrobial peptides with different functional activities

CR Chung, TR Kuo, LC Wu, TY Lee… - Briefings in …, 2020 - academic.oup.com
… On this basis, we specifically investigated the sequence features of AMPs with a range of …
Sequential forward selection was employed to extract potentially informative features that …

Synthetic molecular evolution of antimicrobial peptides

CH Chen, T Bepler, K Pepper, D Fu, TK Lu - Current opinion in …, 2022 - Elsevier
… how peptide structure and activity are related, we anticipate that antimicrobial peptides will
be engineered to have strong potency and distinct functions and that synthetic peptides will …