How CRISPR-Cas system could be used to combat antimicrobial resistance

P Gholizadeh, Ş Köse, S Dao, K Ganbarov… - … and drug resistance, 2020 - Taylor & Francis
… reduce resistance of bacteria to antibiotics. Therefore, this study aims to review using …
CRISPR-Cas system to promote sensitizing bacteria to antibiotics. We envision that CRISPR-Cas

Harnessing the CRISPR-Cas systems to combat antimicrobial resistance

C Duan, H Cao, LH Zhang, Z Xu - Frontiers in Microbiology, 2021 - frontiersin.org
… We also discuss the most common challenges in applying CRISPR-Cas antimicrobials and
… of developing CRISPR-Cas antimicrobials to combat antimicrobial resistance with a focus on …

CRISPR-cas system: biological function in microbes and its use to treat antimicrobial resistant pathogens

MAB Shabbir, MZ Shabbir, Q Wu, S Mahmood… - … and antimicrobials, 2019 - Springer
… to combat the antimicrobial resistance. In this review, we discuss how the newly popular
CRISPR-cas system has been applied to combat antibiotic resistance in both extracellular and …

The application of the CRISPR-Cas system in antibiotic resistance

S Tao, H Chen, N Li, W Liang - Infection and drug resistance, 2022 - Taylor & Francis
resistance. In this review, we will introduce the structure and working mechanism of CRISPR-Cas
… on the relationship between antimicrobial resistance and CRISPR-Cas. Moreover, the …

Bacterial resistance to CRISPR-Cas antimicrobials

RV Uribe, C Rathmer, LJ Jahn, MMH Ellabaan, SS Li… - Scientific reports, 2021 - nature.com
… of resistance described in this manuscript arising after several cycles or years of treatment
using CRISPR-Cas antimicrobialsCas systems would be a good strategy to reduce mutations. …

CRISPR-Cas is associated with fewer antibiotic resistance genes in bacterial pathogens

E Pursey, T Dimitriu, FL Paganelli… - … of the Royal …, 2022 - royalsocietypublishing.org
… These results have promising implications for the delivery of novel technologies to combat
ABR such as phage therapy and CRISPR-Cas antimicrobials, which rely on bypassing …

Microbiota transplantation and/or CRISPR/Cas in the battle against antimicrobial resistance

J Vila - Clinical Microbiology and Infection, 2018 - clinicalmicrobiologyandinfection …
… two approaches to combat antimicrobial resistance. In an … CRISPR/Cas could be used to
specifically sensitize resistant … these two approaches in containing antimicrobial resistance. …

CRISPR-Cas-based antimicrobials: design, challenges, and bacterial mechanisms of resistance

A Mayorga-Ramos, J Zúñiga-Miranda… - ACS Infectious …, 2023 - ACS Publications
… or curing of plasmids encoding antibiotic resistance. In this Review, we provide an overview
of the main CRISPR-Cas systems utilized for the creation of these antimicrobials, as well as …

CRISPR-Cas antimicrobials: challenges and future prospects

E Pursey, D Sünderhauf, WH Gaze, ER Westra… - PLoS …, 2018 - journals.plos.org
Antimicrobial resistance (AMR) poses a serious threat to modern medicine and may render
common infections untreatable. The discovery of new antibiotics has come to a relative …

Using CRISPR-Cas systems as antimicrobials

D Bikard, R Barrangou - Current opinion in Microbiology, 2017 - Elsevier
CRISPR-Cas … & II CRISPR-Cas systems as programmable antimicrobials. We discuss how
they can be readily directed to target undesirable sequences such as antibiotic resistance and …