… Our study showed that oxaliplatin exerts protection against the cytotoxicity of anticancer
drugs via Nrf2, indicating an important role of Nrf2 in oxaliplatin-based chemotherapy. …

Full article: Biophysical and molecular docking insight into interaction mechanism and
thermal stability of human serum albumin isoforms with a semi-synthetic water-soluble …

… oxaliplatin activity was lost after 14 h on incubation with albumin, whereas the anticancer
activity of 3 was maintained over a full 24 h of incubation in the presence of albumin (Fig. 3B…

… Binding to serum albumin represents one of the most efficient … cytotoxic properties of
oxaliplatin, the anticancer activity of our … With regard to blood plasma, treatment with all maleimide …

… present as metabolites in the blood plasma and urine.[31] In … Such redox chemistry of
platinum() anticancer drugs has … can cleave disulfide bonds in human serum albumin,[36] and …

… modifying/alkylating agents (cisplatin and cyclophosphamide) Citation[[65]]… oxaliplatin
demonstrates additive/synergistic activity in combination with many standard anticancer agents in …

… of oxaliplatin (almost 85%–88%) in blood plasma is bound to … of oxaliplatin to serum
albumin is suspected to reduce its anticancer potential (12), and the accumulation of oxaliplatin in …

… drug oxaliplatin have been shown to be potent anticancer compounds maintaining some
central properties of the parental drug … among the most successful anticancer drugs. However, …

… drugs formulated by Abraxis Bioscience, many other labs have experimented with the delivery
of hydrophobic small-molecule anticancer drugs using albumin … -human serum albumin (…

… to the recognized anticancer drugs such as cisplatin, carboplatin, and oxaliplatin. Cell cycle
… such as bovine serum albumin (similar to HSA, human serum albumin) was performed by …