… There is little doubt that the antinociceptive effect of morphine in different animal tests and,
more importantly, its analgesic effects in man are due to its interaction with p-opioid receptors. …

… of selective opioid receptor antagonists has shown that the intrinsic antinociceptive effects of
… (i) naloxonazine, a μ 1 -selective opioid receptor antagonist, or (ii) naltrindole, a δ-selective …

… Consistent with the presence of opioid receptors in the spinal cord, spinally administered
opiates exert robust antinociceptive effects in animal models of pain and in clinical practice as …

… (1) the antinociceptive effects of systemically applied #- and K-opioid agonists in unilateral
hindpaw inflammation and (2) whether peripheral opioid-receptor specific mechanisms might …

… -receptors in effecting antinociception. The present data report that the two pentapeptides
which are relatively selective delta opioid receptor antagonists produce antinociceptive effects …

… agonist, morphine (13.2 nmol) or the (-receptor agonist, [D… effects of these opioid agonists.
The results of this study show that spinal ,-and 6-opioid receptors play a role in antinociception …

… The duration of the antinociceptive effect produced by TRK-820 was … by u-opioid receptor
agonist morphine or other k-opioid receptor agonists. In addition, with four other antinociceptive …

… antinociception by stimulating one type of μ-opioid receptor, whereas endomorphin-2 initially
stimulates different μ-opioid receptors… act on κ-opioid receptors to produce antinociception. …

… that cannabinoid receptor agonists enhance the antinociceptive effects of μ-opioid receptor
… , by efficacy at the μ-opioid receptor, with the cannabinoid receptor agonists Δ 9 -THC and …

… μ-opioid receptor-mediated endogenous opioid neurotransmission may underlie some of
these processes. We examined both baseline μ-opioid receptor … μ-opioid receptor availability in …