[PDF][PDF] A polymorphic antioxidant response element links NRF2/sMAF binding to enhanced MAPT expression and reduced risk of Parkinsonian disorders
… response by occupying cis-acting enhancers containing an antioxidant response element
(… sMAF in tauopathies and a possible role for NRF2 pathway activators in disease prevention. …
(… sMAF in tauopathies and a possible role for NRF2 pathway activators in disease prevention. …
A new ferroptosis inhibitor, isolated from Ajuga nipponensis, protects neuronal cells via activating NRF2-antioxidant response elements (AREs) pathway
… Experimental results demonstrated that ADC effectively prevented ferroptosis through
scavenging free radical and activating NRF2-antioxidant response elements (AREs) pathway. This …
scavenging free radical and activating NRF2-antioxidant response elements (AREs) pathway. This …
Curcumin protects BEAS‑2B cells from PM2.5‑induced oxidative stress and inflammation by activating NRF2/antioxidant response element pathways
S Yang, XL Huang, J Chen… - International …, 2021 - spandidos-publications.com
… signaling cascades and the activation of redox-sensitive … transcription of several antioxidant
and detoxifying enzymes, … , the activation of NRF2/antioxidant response element (ARE) …
and detoxifying enzymes, … , the activation of NRF2/antioxidant response element (ARE) …
Profiling environmental chemicals for activity in the antioxidant response element signaling pathway using a high throughput screening approach
SJ Shukla, R Huang, SO Simmons… - Environmental …, 2012 - ehp.niehs.nih.gov
… ARE activators through Nrf2-dependent and independent mechanisms. The ARE-luc
reporter was constructed using entirely synthetic sequences designed to identify ARE activators …
reporter was constructed using entirely synthetic sequences designed to identify ARE activators …
[HTML][HTML] Nuclear factor-like factor 2-antioxidant response element signaling activation by tert-butylhydroquinone attenuates acute heat stress in bovine mammary …
… factor that binds to the antioxidant response element (ARE) in … antioxidant-defense system,
but whether Nrf2 activation has … ), a well-known Nrf2 activator, could attenuate heat stress-…
but whether Nrf2 activation has … ), a well-known Nrf2 activator, could attenuate heat stress-…
Characterization of Nrf1b, a novel isoform of the nuclear factor-erythroid-2 related transcription factor-1 that activates antioxidant response element-regulated genes
EK Kwong, KM Kim, PJ Penalosa, JY Chan - PLoS One, 2012 - journals.plos.org
… role in the activation of cytoprotective genes through the antioxidant response elements. The
… and accumulates in the nucleus in response to activating signals. Here we characterized a …
… and accumulates in the nucleus in response to activating signals. Here we characterized a …
Transcriptional regulation of rat γ-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element
SV Shenvi, EJ Smith, TM Hagen - Pharmacological research, 2009 - Elsevier
… Computer-based sequence analysis identified three putative antioxidant response elements
… expression plasmid resulted in a 3-fold activation of ARE3-mediated transcription relative to …
… expression plasmid resulted in a 3-fold activation of ARE3-mediated transcription relative to …
Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD (P) H: quinone …
R Venugopal, AK Jaiswal - Proceedings of the National …, 1996 - National Acad Sciences
… DNA binding domain that may be the target of redox regulation by electrophiles and reactive
oxygen species generated due to metabolic activation of xenobiotics and antioxidants (8). …
oxygen species generated due to metabolic activation of xenobiotics and antioxidants (8). …
Induced expression of drug metabolizing enzymes by preventive agents: role of the antioxidant response element
RA Lubet, R Yao, CJ Grubbs, M You, Y Wang - Chemico-biological …, 2009 - Elsevier
… receptors (CAR, AhR) as well as antioxidant response elements (AREs), included Phase I/II …
) is a surrogate for overall Phase II inducing (antioxidant) and potential anti-tumor activity. …
) is a surrogate for overall Phase II inducing (antioxidant) and potential anti-tumor activity. …
Identification of age‐specific Nrf2 binding to a novel antioxidant response element locus in the Gclc promoter: a compensatory means for the loss of glutathione …
SV Shenvi, E Smith, TM Hagen - Aging cell, 2012 - Wiley Online Library
… to show that Nrf2 bound to the active antioxidant response element (ARE) of the catalytic
subunit of … No evidence of Bach1 binding to this element was observed. Thus, only co-activating …
subunit of … No evidence of Bach1 binding to this element was observed. Thus, only co-activating …