Regulatory mechanisms controlling gene expression mediated by the antioxidant response element

T Nguyen, PJ Sherratt, CB Pickett - Annual review of …, 2003 - annualreviews.org
… exposed to electrophilic compounds and phenolic antioxidants. Induction of these enzymes
… , the antioxidant response element or ARE, found in the promoter of the enzyme's gene. The …

Antioxidant response element

AK Jaiswal - Biochemical pharmacology, 1994 - Elsevier
… Hydrogen peroxide (H202) has been shown to induce gene expression mediated by a
perfect APl element (TRE) [25] and ARE [24-261 and may be an important intermediate in the …

Role of Nrf1 in antioxidant response element-mediated gene expression and beyond

M Biswas, JY Chan - Toxicology and applied pharmacology, 2010 - Elsevier
… in activation of genes regulated by the antioxidant response element, involvement of Nrf1 …
gene expression analysis in knockout cells and animals. These targets of Nrf1 include genes

[HTML][HTML] Antioxidant response elements: Discovery, classes, regulation and potential applications

A Raghunath, K Sundarraj, R Nagarajan, F Arfuso… - Redox biology, 2018 - Elsevier
… Such competition encouraged researchers to identify and distinguish the transcription factors
that bind to TRE and ARE and the regulation of the gene expression by these two elements

Functional antioxidant responsive elements

WW Wasserman, WE Fahl - Proceedings of the National …, 1997 - National Acad Sciences
… as a composite regulatory site, where multiple transcription factors interact, is presented to
account for the complex characteristics of ARE-mediated chemoprotective gene expression. …

In Vitro and in Vivo Regulation of Antioxidant Response Element-Dependent Gene Expression by Estrogens

PJ Ansell, C Espinosa-Nicholas, EM Curran… - …, 2004 - academic.oup.com
expression is regulated by a cis-acting DNA sequence, the antioxidant response element (…
not 17β-estradiol, could regulate ARE-mediated gene transcription. Our goal was to determine …

… characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD (P) H: quinone oxidoreductase1 gene

S Dhakshinamoorthy, AK Jaiswal - Oncogene, 2001 - nature.com
Antioxidant response element (ARE) and nuclear transcription factor Nrf2 are known to regulate
expression and coordinated induction of NQO1 and other detoxifying enzyme genes in …

[HTML][HTML] Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism

R Yu, C Chen, YY Mo, V Hebbar, ED Owuor… - Journal of Biological …, 2000 - ASBMB
… at the transcriptional level and is regulated by acis-acting element that is present in the
promoters of detoxifying enzyme genes defined as an antioxidant response element (ARE) ( …

Nrf2 and c-Jun regulation of antioxidant response element (ARE)-mediated expression and induction of γ-glutamylcysteine synthetase heavy subunit gene

J Jeyapaul, AK Jaiswal - Biochemical pharmacology, 2000 - Elsevier
… Ya genes contain a cis-acting DNA element designated as the antioxidant response element
(… that ARE-mediated γ-GCS gene expression and induction in response to xenobiotics and …

Effects of glutathione on antioxidant response element-mediated gene expression and apoptosis elicited by sulforaphane

BR Kim, R Hu, YS Keum, V Hebbar, G Shen, SS Nair… - Cancer research, 2003 - AACR
… induce the expression of the antioxidant response element (ARE)-related genes and cause
… (GSH) in the activations of ARE-mediated gene expression, apoptosis, and the activation of c-…