Molecular mechanisms of Nrf2‐mediated antioxidant response

W Li, AN Kong - Molecular Carcinogenesis: Published in …, 2009 - Wiley Online Library
… of cellular antioxidant defense is implied in the etiology of diverse diseases, including cancer
4, 5. Gene knockout mice deficient in antioxidant response … of the antioxidant response may …

[HTML][HTML] Antioxidant responses and cellular adjustments to oxidative stress

C Espinosa-Diez, V Miguel, D Mennerich, T Kietzmann… - Redox biology, 2015 - Elsevier
… cellular and tissular settings where antioxidant responses are major players we highlight …
considered important molecular mechanisms mediating many antioxidant responses, whereas …

Chemical and molecular mechanisms of antioxidants: experimental approaches and model systems

JM Lü, PH Lin, Q Yao, C Chen - … of cellular and molecular …, 2010 - Wiley Online Library
… of enzyme activities by antioxidants have opened a new door for us to further understand
the molecular mechanisms of action of antioxidants. Since the 1990s, antioxidant research has …

Regulatory mechanisms controlling gene expression mediated by the antioxidant response element

T Nguyen, PJ Sherratt, CB Pickett - Annual review of …, 2003 - annualreviews.org
… This review focuses on the molecular mechanisms whereby the trancriptional activation
mediated by the interaction between the ARE and NF-E2-related factor 2 (Nrf2) is regulated. …

Molecular mechanisms of zinc as a pro-antioxidant mediator: clinical therapeutic implications

AS Prasad, B Bao - Antioxidants, 2019 - mdpi.com
… In this article, we will discuss the molecular mechanisms of zinc as an anti-oxidative stress
agent or mediator in the body. We will also discuss the applications of zinc supplementation …

Antioxidant response element

AK Jaiswal - Biochemical pharmacology, 1994 - Elsevier
… These investigations will help us understand the factors regulating oxidant and antioxidant
responses in eukaryotic cells. Recently, Ref-1 protein has been identified as the major Jun-…

Molecular mechanisms of neuroprotection by two natural antioxidant polyphenols

MR Campos-Esparza, MV Sánchez-Gómez, C Matute - Cell calcium, 2009 - Elsevier
… two natural polyphenol antioxidants, mangiferin and morin, are neuroprotective in a model
of ischemic brain damage. In this study, we analyzed the molecular mechanisms underlying …

Molecular mechanisms of hypertension—reactive oxygen species and antioxidants: a basic science update for the clinician

AC Montezano, RM Touyz - Canadian Journal of Cardiology, 2012 - Elsevier
… in the molecular mechanisms associated with cardiovascular and renal injury in hypertension.
Although clinical trials failed to show beneficial antihypertensive effects of antioxidants, …

Small molecule modulators of antioxidant response pathway

W Hur, NS Gray - Current opinion in chemical biology, 2011 - Elsevier
… been observed from phenolic antioxidants since the early … antioxidants was identified and
named ‘antioxidant response … The phenolic antioxidants have an intrinsic antioxidant activity …

The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress

T Nguyen, CS Yang, CB Pickett - Free Radical Biology and Medicine, 2004 - Elsevier
… to these compounds is mediated by the cis-acting antioxidant response element (ARE)
found in the promoter of the encoding genes. The transcription factor NF-E2-related factor 2, or …