Antiphospholipid antibodies and the antiphospholipid syndrome: pathogenic mechanisms

SS Pierangeli, PP Chen, E Raschi… - … in thrombosis and …, 2008 - thieme-connect.com
Antiphospholipid antibodies (Abs) are associated with thrombosis and are a risk factor for …
Fluvastatin inhibits upregulation of tissue factor expression by antiphospholipid antibodies

[HTML][HTML] Thrombotic risk factors, antithrombotic therapy, and outcomes of asymptomatic carriers of antiphospholipid antibodies and patients with antiphospholipid …

G Abu-Zeinah, C Oromendia, MT De Sancho - Blood, 2017 - Elsevier
… occurring in a young male without the aforementioned risk factors. Thirteen patients (11%) …
disease and Black race were risk factors for thrombotic events in antiphospholipid patients. …

[HTML][HTML] Non-criteria antiphospholipid antibodies: Risk factors for endothelial dysfunction in women with pre-eclampsia

L Belmar Vega, G Fernandez Fresnedo, J Irure Ventura… - Life, 2020 - mdpi.com
… morbidity and mortality is the antiphospholipid syndrome (APS) [10]. APS is a systemic
autoimmune disorder defined by the persistent presence of antiphospholipid antibodies (aPL) in …

Antiphospholipid antibodies disappearance in primary antiphospholipid syndrome: thrombosis recurrence

G Medina, E Briones-García, MP Cruz-Domínguez… - Autoimmunity …, 2017 - Elsevier
… These studies suggested the possibility of anticoagulation discontinuation in PAPS patients
with low-risk and venous thrombosis with a concomitant risk factor that turned persistently …

[HTML][HTML] Antiphospholipid antibodies as a risk factor for atherosclerotic events in renal transplant recipients

D Ducloux, E Bourrinet, G Motte, JM Chalopin - Kidney international, 2003 - Elsevier
… Both traditional and nontraditional cardiovascular risk factors are very prevalent in our
population and contribute for this increased incidence of atherosclerotic events. Nevertheless, we …

Antiphospholipid antibodies in patients with coronary artery disease: new cardiac risk factors?

TP Greco, ANNM CONTI‐KELLY… - Annals of the New …, 2007 - Wiley Online Library
Antiphospholipid antibodies (aPL) have been implicated in the pathogenesis of coronary
artery disease (CAD). We evaluated the presence of aPL in patients with chest pain/acute …

Thromboembolic risk in patients with high titre anticardiolipin and multiple antiphospholipid antibodies

C Neville, J Rauch, J Kassis, ER Chang… - Thrombosis and …, 2003 - thieme-connect.com
… Our findings demonstrate that, after adjustment for cardiovascular risk factors, the presence
of aCL is associated with thrombosis. Furthermore, higher titres of aCL increase the odds for …

Antiphospholipid antibodies and antiphospholipid syndrome in patients presenting with immune thrombocytopenic purpura: a prospective cohort study

R Diz-Kucukkaya, A Hacıhanefioglu… - Blood, The Journal …, 2001 - ashpublications.org
… Our data demonstrate that persistent positivity for LA is an important risk factor for the
development of APS in patients who present with ITP. Further studies are required to definitively …

Risky business: the interpretation, use, and abuse of antiphospholipid antibody tests in clinical practice

RAS Roubey - Lupus, 2010 - journals.sagepub.com
Antiphospholipid antibodies (aPL) are best considered as risk factors. aPL are not diagnostic
tests and considering them as such can be misleading and may direct attention away from …

Additional risk factors associated with thrombosis and pregnancy morbidity in a unique cohort of antiphospholipid antibody-positive patients

C Li, Y Zuo, S Zhang, UE Makris, DR Karp… - Chinese medical …, 2022 - mednexus.org
… and epidemiological risks of arterial thrombosis, venous thrombosis, and pregnancy
morbidities in a large cohort of persistent antiphospholipid antibodies (aPLs)-positive carriers. …