Low-abundance drug-resistant viral variants in chronically HIV-infected, antiretroviral treatment–naive patients significantly impact treatment outcomes
BB Simen, JF Simons, KH Hullsiek… - The Journal of …, 2009 - academic.oup.com
… larger proportion of HIV-infected, treatment-naive persons as harboring drug-resistant viral
variants. Among participants who initiated treatment with the NNRTI strategy, the risk of VF …
variants. Among participants who initiated treatment with the NNRTI strategy, the risk of VF …
[HTML][HTML] Low-abundance HIV drug-resistant viral variants in treatment-experienced persons correlate with historical antiretroviral use
… Antiretroviral treatment histories were obtained by chart review and correlated with drug-…
antiretrovirals in 17 of 22 subjects (77%). When correlated with subjects' antiretroviral treatment …
antiretrovirals in 17 of 22 subjects (77%). When correlated with subjects' antiretroviral treatment …
Transmission of antiretroviral-drug-resistant HIV-1 variants
S Yerly, L Kaiser, E Race, JP Bru, F Clavel, L Perrin - The Lancet, 1999 - thelancet.com
… antiretroviral treatment. The main causes for the emergence of drug-resistant HIV-1 variants
include suboptimum treatment … in an increased transmission of these viral variants. The pre-…
include suboptimum treatment … in an increased transmission of these viral variants. The pre-…
Pre-existing minority drug-resistant HIV-1 variants, adherence, and risk of antiretroviral treatment failure
R Paredes, CM Lalama, HJ Ribaudo… - The Journal of …, 2010 - academic.oup.com
… Of note, 70% of subjects with minority Y181C variants achieved long-term viral suppression.
… -resistant variants significantly increased the risk of virologic failure of initial antiretroviral …
… -resistant variants significantly increased the risk of virologic failure of initial antiretroviral …
Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis
… viral variants in chronically HIV-infected, antiretroviral treatment-naive patients significantly
impact treatment … HIV-1 variants, adherence, and risk of antiretroviral treatment failure. …
impact treatment … HIV-1 variants, adherence, and risk of antiretroviral treatment failure. …
Prevalence of R5 and X4 HIV variants in antiretroviral treatment experienced patients with virologic failure
P Ferrer, M Tello, L Montecinos, R Tordecilla… - Journal of Clinical …, 2014 - Elsevier
… the prevalence of R5 and X4 variants among Chilean patients under antiretroviral therapy
and virological failure and investigate variables such as plasma viral load (pVL) and CD4 cell …
and virological failure and investigate variables such as plasma viral load (pVL) and CD4 cell …
[HTML][HTML] Hepatitis B virus variants in an HIV-HBV co-infected patient at different periods of antiretroviral treatment with and without lamivudine
EA Santos, MVF Sucupira, J Arabe, SA Gomes - BMC infectious diseases, 2004 - Springer
… HBV variants and genetic patterns of lamivudine resistant HBV strains in a patient co-infected
with HIV-1 at different periods of an antiretroviral treatment with and without lamivudine. …
with HIV-1 at different periods of an antiretroviral treatment with and without lamivudine. …
Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study
… the basis of: long-term viral suppression; treatment with nelfinavir (1250 mg twice daily) or
efavirenz (600 mg per day); antiretroviral treatment that suppressed viral load to less than 400 …
efavirenz (600 mg per day); antiretroviral treatment that suppressed viral load to less than 400 …
Transmission of HIV-1 drug-resistant variants: prevalence and effect on treatment outcome
MR Jakobsen, M Tolstrup, OS Søgaard… - Clinical infectious …, 2010 - academic.oup.com
… type 1 (HIV-1) drug resistance is an important threat to the overall success of antiretroviral …
virological failure (defined as detectable viral load after 6 months of treatment); thus, our data …
virological failure (defined as detectable viral load after 6 months of treatment); thus, our data …
[HTML][HTML] Minority HIV-1 drug resistance mutations are present in antiretroviral treatment–naïve populations and associate with reduced treatment efficacy
JA Johnson, JF Li, X Wei, J Lipscomb, D Irlbeck… - PLoS …, 2008 - journals.plos.org
… levels of virus variants with 1–3 drug-resistance mutations; 2% of them carried viruses resistant
… one additional minority drug-resistant variant, often a viral variant that was resistant to a …
… one additional minority drug-resistant variant, often a viral variant that was resistant to a …
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