… potent antitumor activity causing regression, growth arrest, or substantially reduced growth
of … To predict the target SU11248 exposure required to achieve antitumor activity in mouse …

… This antitumor effect was significantly different to the GEO tumor growth in mice treated …
We next evaluated whether treatment with ZD6474 could have antitumor activity in GEO tumors …

… which bind specifically to receptors for growth factors. Our studies dem onstrated that anti-growth
factor receptor mAbs can block the access of growth factors to their receptors on tumor …

… factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor
(… In this study, we have evaluated the antiangiogenic and antitumor activity of monoclonal …

… -expressing Cl96 cells possessed antitumor activity after adoptive transfer comparable to
transduced primary cells. To enable the evaluation of the activity of the chimeric TCR against …

… growth (compared with that in control mice; P <.00001) and suppressed cancer cell production
of autocrine growth factors, … ) factors, such as vascular endothelial growth factor and basic …

… express functional EGFR, the antiproliferative activity of MAb C225 in combination with …
antitumor activity in these malignancies. A dose-dependent supraadditive increase of growth …

Interleukin-15 is a new cytokine that stimulates the proliferation of T cells and other cells of
the immune system. Some of the biological properties of interleukin-15 overlap that of …

… We evaluated the clinical efficacy and impact on serum vascular endothelial growth factor
(VEGF) levels of low-dose oral MTX and CTX in patients with metastatic breast cancer. MTX …

… activity in … the antitumor activity spectrum of MV833 against 27 human tumors transplanted
in nude mice and show that anti-VEGF antibody has the potential to inhibit the growth of many …