Strategies of development of antiviral agents directed against influenza virus replication

HP Hsieh, JTA Hsu - Current pharmaceutical design, 2007 - ingentaconnect.com
influenza infections have occurred in humans [4]. The great concern is the possibility of a
highly virulent strain of influenza virus, such as the H5N1 avian influenza virus, … , influenza virus

Antiviral agents active against influenza A viruses

E De Clercq - Nature reviews Drug discovery, 2006 - nature.com
… This article reviews agents that have been shown to have activity against influenza A viruses
… of an avian influenza virus with a human influenza virus, as occurred in 1957 with the 'Asian …

Antivirals and resistance: influenza virus

MG Ison - Current opinion in virology, 2011 - Elsevier
… of influenza; several other classes of antiviralsantivirals is the emergence of resistant
mutants. In this paper, we will review the currently approved and investigational antiviral agents

Antiviral agents against influenza viruses

S Park, JI Kim, MS Park - Journal of Bacteriology and …, 2012 - synapse.koreamed.org
… of seasonal and highly pathogenic influenza viruses including resistant variants. In this
review, we provide insights of antiviral drugs for the control and prevention of influenza viruses. …

The use of antiviral agents for the management of severe influenza

JR Smith, RE Ariano, S Toovey - Critical Care Medicine, 2010 - journals.lww.com
… The pH1N1 2009 virus is now the predominant influenza virus in the temperate zones of
the northern and southern hemispheres, although infection rates in the latter have returned to …

Developing new antiviral agents for influenza treatment: what does the future hold?

F Hayden - Clinical Infectious Diseases, 2009 - academic.oup.com
antiviral agents for the treatment of influenza: antiviral resistance; limited antiviral efficacy in
severe cases of influenza… of antiviral agents directed against influenza virus replication. Curr …

Antiviral strategies against influenza virus: towards new therapeutic approaches

A Loregian, B Mercorelli, G Nannetti… - Cellular and molecular …, 2014 - Springer
… need for developing new antiviral strategies with novel … Several new classes of antiviral
agents targeting viral replication … the virus and/or the host cell for counteracting influenza virus

Emerging antiviral strategies to interfere with influenza virus entry

E Vanderlinden, L Naesens - Medicinal research reviews, 2014 - Wiley Online Library
… or the neuraminidase inhibitor oseltamivir, novel antiviral agents with an original mode of …
the influenza virus entry process, which consists of the following steps: attachment of the viral

Influenza virus resistance to antiviral agents: a plea for rational use

GA Poland, RM Jacobson… - Clinical infectious …, 2009 - academic.oup.com
… pressure on influenza viruses and diminish the development of antiviral resistance, as well
… to influenza. In conclusion, continued use of antiviral monotherapy against influenza virus is …

Emerging cellular targets for influenza antiviral agents

KH Müller, L Kakkola, AS Nagaraj, AV Cheltsov… - Trends in …, 2012 - cell.com
… An influenza virus particle docks with the cell membrane as hemagglutinin (HA) proteins
link to cell-surface receptors. The cell membrane folds inward, which causes the …