… The clinical impact of multiclass drug resistance on retreatment outcomes is unclear, but
concerning data are starting to emerge. In phase 3 trials, retreatment with glecaprevir (NS3 …

… ] discusses the development and possible clinical impact of the novel influenza virus PA
endonuclease inhibitor baloxavir marboxil with particular emphasis on clinical trial data and the …

… We wished to document together the temporal changes in ART use and ARV choices, the
factors associated with changes in ART, the impact initially of ART on clinical and …

… for other clinical infectious diseases. The selection includes antiviral drugs, boosters and
a group of miscellaneous drugs approved for other uses. The selected antiviral drugs are …

… For HBV, the patterns of antiviral drug resistance in chronic hepatitis are complex and the …
properties at the entry step and as antigenic proteins, and the subsequent clinical impact. …

… as first-line antiretroviral therapy (ART), the of baseline genotypes is uncertain. … We used
the Cost-effectiveness of Preventing AIDS Complications model to examine the clinical impact …

… Other various antiviral agents have been utilized in clinical trials to determine their impacts
against SARS-CoV-2. Galidesivir, as a nucleoside analogue and a protease inhibitor, is a …

… establishing the susceptibility of KSHV to available antiviral drugs. Latently infected BCBL-1
cells … We assayed the ability of the antivirals to block KSHV production, as measured by the …

… antiretroviral drug pharmacokinetics in older persons. The authors review articles from PubMed
(search terms: elderly, antiretroviral, … changes that could impact ARV drug PK. However, …

… in clinical trials because phenotyping assays do not always reliably predict clinical … seeking
approval using the Animal Rule, metagenomics studies looking at the impact of antivirals and …