Antiviral peptides as promising therapeutics against SARS-CoV-2

SM Chowdhury, SA Talukder, AM Khan… - The Journal of …, 2020 - ACS Publications
… , only few ACE-2-based peptides were screened and proposed. In … antiviral peptides
that were known to work against SARS-CoV-1, targeting the RBD of the S protein of SARS-CoV-2. …

[HTML][HTML] Compelling evidence for the activity of antiviral peptides against SARS-CoV-2

M Tonk, D Růžek, A Vilcinskas - Viruses, 2021 - mdpi.com
coronavirus 2 (SARS-CoV-2) is a β-coronavirus that emerged in late 2019 from the Wuhan
region of China [1,2… Enfuvirtide (Fuzeon or T-20) was the first antiviral peptide approved for …

Potential role of peptide-based antiviral therapy against SARS-CoV-2 infection

BK Maiti - ACS pharmacology & translational science, 2020 - ACS Publications
coronavirus 2 (SARS-CoV-2) infectious disease (COVID-19) … is an urgent requirement of
suitable antiviral agent/therapy to … of SARS-CoV-2 infection is the crosstalk between the SARS-…

[HTML][HTML] Antiviral peptides against SARS-CoV-2: therapeutic targets, mechanistic antiviral activity, and efficient delivery

RZ Essa, Y Wu, K Batumalaie, M Sekar, C Poh - Pharmacological Reports, 2022 - Springer
… novel therapeutics against SARS-CoV-2. Despite these benefits, antiviral peptides are
particularly … of using nanotechnology to deliver antiviral peptides against SARS-CoV-2 infection. …

[HTML][HTML] Antiviral cyclic peptides targeting the main protease of SARS-CoV-2

J Johansen-Leete, S Ullrich, SE Fry, R Frkic… - Chemical …, 2022 - pubs.rsc.org
peptide inhibitors of SARS-CoV-2 M pro , we sought to utilize RaPID, which allows the screening
of >10 12 cyclic peptides … However, functional SARS-CoV-2 M pro is a homodimer with …

[HTML][HTML] In silico design of antiviral peptides targeting the spike protein of SARS-CoV-2

R Ling, Y Dai, B Huang, W Huang, J Yu, X Lu, Y Jiang - Peptides, 2020 - Elsevier
… infection and also prepare for future clinical application research for SARS-CoV-2 therapy.
We will further simulate the antivirus peptide with modification and test the blocking effect in …

[HTML][HTML] Peptide and peptide-based inhibitors of SARS-CoV-2 entry

D Schütz, YB Ruiz-Blanco, J Münch, F Kirchhoff… - Advanced drug delivery …, 2020 - Elsevier
… or exert broad antiviral activity. Here, we summarize the current status of peptides inhibiting
SARS-CoV-2 entry and outline the strategies used to design peptides targeting the ACE2 …

[HTML][HTML] The potential of antiviral peptides as COVID-19 therapeutics

ASK Mahendran, YS Lim, CM Fang, HS Loh… - Frontiers in …, 2020 - frontiersin.org
… In search of an effective antiviral against COVID-19, we believe AVPs could represent
one of the potential classes of new antiviral agents against SARS-CoV-2. It is fascinating to …

[HTML][HTML] Antiviral peptides against the main protease of SARS-CoV-2: A molecular docking and dynamics study

S Mahmud, S Biswas, GK Paul, MA Mita… - Arabian journal of …, 2021 - Elsevier
… In our study, we only examined those peptide molecules with known antiviral activity.
Based on antiviral activity, we screened 215 antiviral peptides from 5820 peptides. Additional …

[HTML][HTML] Potential antiviral peptides targeting the SARS-CoV-2 spike protein

I Khater, A Nassar - BMC Pharmacology and Toxicology, 2022 - Springer
… On the other hand, few approved antiviral treatments demonstrated … SARS-CoV-2 papin-like
protease. The current work aims to design an in-silico peptide inhibitor of the SARS-CoV-2