The mechanism and therapy of aortic aneurysms

J Gao, H Cao, G Hu, Y Wu, Y Xu, H Cui, HS Lu… - … and targeted therapy, 2023 - nature.com
… the pathogenesis of aneurysms to find new targets for diagnosis and treatment. To better
understand aortic aneurysm, this review elaborates on the discovery history of aortic aneurysm, …

Pathogenic mechanisms and the potential of drug therapies for aortic aneurysm

B Liu, DJ Granville, J Golledge… - American Journal of …, 2020 - journals.physiology.org
… novel contributors to aneurysm formation and progression. The … aneurysm pathogenesis.
An update of clinical trials focusing on therapeutic strategies to slow abdominal aortic aneurysm

Mechanisms of aortic aneurysm formation: translating preclinical studies into clinical therapies

FM Davis, DL Rateri, A Daugherty - Heart, 2014 - heart.bmj.com
aneurysmal degeneration of chronic aortic dissection for which a detailed account on
mechanisms of formation and therapeutic … ascending aorta, this section will focus on mechanisms

Medical therapy of thoracic aortic aneurysms: are we there yet?

P Danyi, JA Elefteriades, IS Jovin - Circulation, 2011 - Am Heart Assoc
… medical therapies for aortic aneurysms and attempts to determine whether medical therapy
for … Molecular mechanisms of aneurysm formation and the effects of different medications. …

Abdominal aortic aneurysm: novel mechanisms and therapies

FM Davis, DL Rateri, A Daugherty - Current opinion in cardiology, 2015 - journals.lww.com
… Abdominal aortic aneurysm (AAA) is a pathological condition of permanent dilation that
portends the potentially fatal consequence of aortic rupture. This review emphasizes recent …

Therapies for thoracic aortic aneurysms and acute aortic dissections: old controversies and new opportunities

DM Milewicz, F Ramirez - Arteriosclerosis, Thrombosis, and …, 2019 - Am Heart Assoc
… Similar stage-specific mechanisms may diversify TGFβ action in thoracic aortic disease. For
… pathogenesis of thoracic aortic aneurysm, there are still limited therapeutic options to delay …

Aortic aneurysms: current pathogenesis and therapeutic targets

MJ Cho, MR Lee, JG Park - Experimental & Molecular Medicine, 2023 - nature.com
… , there are unknown pathogenic mechanisms involved in cellular heterogeneity and …
mechanisms of aortic aneurysms, which may enhance our understanding of aortic aneurysms

Abdominal aortic aneurysm: update on pathogenesis and medical treatments

J Golledge - Nature Reviews Cardiology, 2019 - nature.com
… Currently, no drug therapy is available for abdominal aortic aneurysm (AAA), which drives a
… important research avenue to explore pathogenic mechanisms and test potential therapies. …

Pharmacological therapy of abdominal aortic aneurysm: an update

Y Wang, Z Liu, J Ren, M Xiang - Current vascular …, 2018 - ingentaconnect.com
aortic aneurysm (AAA), a progressive abdominal aortic dilation … Current evidence of
medical therapy is lowquality, and no … of the biological mechanisms underlying the disease. …

Updates of recent aortic aneurysm research

FM Davis, A Daugherty, HS Lu - Arteriosclerosis, thrombosis, and …, 2019 - Am Heart Assoc
… is a hallmark of aortic aneurysm formation, the underlying mechanisms behind this remodeling
… Effects of statin therapy on abdominal aortic aneurysm growth: a meta-analysis and meta-…