Matrix metalloproteinase in abdominal aortic aneurysm and aortic dissection

EM Maguire, SWA Pearce, R Xiao, AY Oo, Q Xiao - Pharmaceuticals, 2019 - mdpi.com
… survival rates and elevated mortality rates for survivors of aortic rupture [1,2]. Importantly…
aorta, whereas the term ‘aortic dissection’ refers to the process of intimal tearing within the aortic

Thoracic aortic dissection: are matrix metalloproteinases involved?

X Zhang, YH Shen, SA LeMaire - Vascular, 2009 - journals.sagepub.com
dissection and subsequent aneurysm formation and rupture. Dissection is associated with
degeneration of the aortic … -called matrix metalloproteinases (MMPs)-in dissected aortic tissue, …

Matrix metalloproteinase levels in chronic thoracic aortic dissection

X Zhang, D Wu, JC Choi, CG Minard, X Hou… - Journal of Surgical …, 2014 - Elsevier
matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) can lead to aortic
wall … resulting from chronic descending thoracic aortic dissection have elevated tissue and …

Collagen and elastin degradation by matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in aortic dissection

T Ishii, N Asuwa - Human pathology, 2000 - Elsevier
… of acute aortic dissection (AD) was ultrastructurally and … catabolic matrix metalloproteinases
(MMPs)-I, -2, -3, and -9 and their inhibitors, the tissue inhibitors of matrix metalloproteinase (…

Matrix metalloproteinases and acute aortic dissection: Et Tu, Brute?

H Takagi, Y Hari, K Nakashima, T Kuno… - … and thoracic surgery, 2020 - academic.oup.com
… To summarize the present evidence for the association of matrix metalloproteinases (MMPs)
with acute aortic dissection (AAD), we performed the first meta-analysis of all currently …

Stanford-A acute aortic dissection, inflammation, and metalloproteinases: a review

N Cifani, M Proietta, L Tritapepe, C Di Gioia… - Annals of …, 2015 - Taylor & Francis
… role in triggering and maintaining the intraparietal inflammatory/matrix degrading processes
underlying ascending thoracic aortic dissection, both in patients with ITCD and in those with …

Expression of matrix metalloproteinase-12 in aortic dissection

Y Song, Y Xie, F Liu, C Zhao, R Yu, S Ban, Q Ye… - BMC cardiovascular …, 2013 - Springer
Background Aortic dissection(AD) is an acute process of large blood vessels characterized
by dangerous pathogenic conditions and high disability and high mortality. The pathogenesis …

Decreased tissue inhibitor of metalloproteinase-2/matrix metalloproteinase ratio in the acute phase of aortic dissection

T Manabe, K Imoto, K Uchida, C Doi, Y Takanashi - Surgery today, 2004 - Springer
… media, and matrix metalloproteinases (MMPs) are enzymes that degrade the extracellular
matrix of the aorta. This study examines MMPs in patients with acute aortic dissection (AAD) in …

Increased tissue microarray matrix metalloproteinase expression favors proteolysis in thoracic aortic aneurysms and dissections

GJ Koullias, P Ravichandran, DP Korkolis… - The Annals of thoracic …, 2004 - Elsevier
BACKGROUND: Little information is available regarding the role of matrix metalloproteinases
(MMPs) in thoracic aortic aneurysms and dissections. We applied tissue microarray …

Neutrophil-derived matrix metalloproteinase 9 triggers acute aortic dissection

T Kurihara, R Shimizu-Hirota, M Shimoda, T Adachi… - Circulation, 2012 - Am Heart Assoc
… Acute aortic dissection (AAD) is a life-threatening vascular disease without effective
pharmaceutical therapy. Matrix metalloproteinases (MMPs) are implicated in the development of …