[HTML][HTML] Comparison of the effects of apixaban and rivaroxaban on prothrombin and activated partial thromboplastin times using various reagents

BJ Dale, JS Ginsberg, M Johnston, J Hirsh… - Journal of Thrombosis …, 2014 - Elsevier
… Although there is information on the effects of rivaroxaban and apixaban on the … to apixaban
but sensitive to rivaroxaban 2 . To confirm these findings, we added apixaban or rivaroxaban

Comparison of the effect of the anti‐Xa direct oral anticoagulants apixaban, edoxaban, and rivaroxaban on coagulation assays

R Gosselin, RP Grant… - International journal of …, 2016 - Wiley Online Library
… screening tests: the prothrombin times (PT) or activated partial thromboplastin time (APTT), …
of commonly used PT and APTT reagents to rivaroxaban, apixaban, and edoxaban, (ii) to …

[HTML][HTML] Dissociation between the pharmacokinetics and pharmacodynamics of once‐daily rivaroxaban and twice‐daily apixaban: a randomized crossover study

R Kreutz, PB Persson, D Kubitza, K Thelen… - Journal of Thrombosis …, 2017 - Elsevier
… , relative to baseline, on inhibition of prothrombin time and activated partial thromboplastin
time. (A) Prothrombin time and (B) Activated partial thromboplastin time. Data are presented …

Effects of thromboprophylactic doses of apixaban and rivaroxaban on coagulation and thrombin generation in association with total hip replacement

TA Helin, L Virtanen, M Manninen, J Leskinen… - Journal of thrombosis …, 2017 - Springer
… However, with apixaban, after an initial decrease, ETP did not differ … apixaban 112 ng/mL,
p = 0.005). In conclusion, due to different dosing and pharmacology rivaroxaban and apixaban

The effect of the direct factor Xa inhibitors apixaban and rivaroxaban on haemostasis tests: a comprehensive assessment using in vitro and ex vivo samples

R Bonar, EJ Favaloro, S Mohammed, M Ahuja… - Pathology, 2016 - Elsevier
… given apixaban and rivaroxaban for various therapeutic reasons. The … time (PT) and activated
partial thromboplastin time (APTT) show better sensitivity with rivaroxaban than apixaban. …

Influence of DOAC Stop on coagulation assays in samples from patients on rivaroxaban or apixaban

S Platton, C Hunt - International Journal of Laboratory …, 2019 - Wiley Online Library
… Samples from patients anticoagulated with either rivaroxaban, apixaban or no anticoagulant
were tested for prothrombin time (PT), activated partial thromboplastin time (APTT), DOAC-…

Association rate constants rationalise the pharmacodynamics of apixaban and rivaroxaban

G Jourdi, V Siguret, AC Martin… - Thrombosis and …, 2015 - thieme-connect.com
… Comparison of the effects of apixaban and rivaroxaban on prothrombin and activated
partial thromboplastin times using various reagents. J Thromb Haemost 2014; 12: 1–6. 11. …

[HTML][HTML] Favorable therapeutic index of the direct factor Xa inhibitors, apixaban and rivaroxaban, compared with the thrombin inhibitor dabigatran in rabbits

PC Wong, EJ Crain, CA Watson, B Xin - Journal of Thrombosis and …, 2009 - Elsevier
thromboplastin time (aPTT) reagent Actin®, prothrombin time (PT) reagent Thromboplastin C
Plus and thrombin time (… Apixaban, rivaroxaban and dabigatran were synthesized at Bristol–…

An observational study of the factor Xa inhibitors rivaroxaban and apixaban as reported to eight poison centers

HA Spiller, JB Mowry, A Aleguas Jr, JRK Griffith… - Annals of emergency …, 2016 - Elsevier
… testing of prothrombin time and partial thromboplastin time, but our … The prothrombin time
and partial thromboplastin time were … with rivaroxaban and in no patients’ results with apixaban

[PDF][PDF] Practical management of bleeding due to the anticoagulants dabigatran, rivaroxaban, and apixaban

MD ADEWALE FAWOLE - Cleveland Clinic Journal of Medicine, 2013 - cdn.mdedge.com
… The activated partial thromboplastin time The activated partial thromboplastin time (aPTT)
is a measure of the activity of the in trinsic pathway of the coagulation cascade. Dabigatran. …