[HTML][HTML] Simultaneous activation of apoptosis and inflammation in pathogenesis of septic shock: a hypothesis

VD Joshi, DV Kalvakolanu, AS Cross - FEBS letters, 2003 - Elsevier
… to the pathogenesis of septic shock is poorly understood. Here, we identify apoptosis and
inflammation as dual pathogenic factors involved in various animal models of septic shock and …

Lymphocyte apoptosis, caspase activation and inflammatory response in septic shock

G Delogu, G Famularo, G Tellan, M Marandola… - Infection, 2008 - Springer
apoptosisinflammation response in septic shock. Materials and Methods: Blood samples
were obtained within 24 h after diagnosis of septic shock from 16 patients to measure apoptosis

[HTML][HTML] … lactate clearance is associated with biomarkers of inflammation, coagulation, apoptosis, organ dysfunction and mortality in severe sepsis and septic shock

HB Nguyen, M Loomba, JJ Yang, G Jacobsen… - … of inflammation, 2010 - Springer
… the association of early lactate clearance with selected inflammatory, coagulation, apoptosis
response biomarkers and organ dysfunction scores in severe sepsis and septic shock. …

NF-κB activation as a pathological mechanism of septic shock and inflammation

SF Liu, AB Malik - … Journal of Physiology-Lung Cellular and …, 2006 - journals.physiology.org
… Inappropriate NF-κB activation is one of the pathogenic mechanisms of a list of diseases,
particularly those with inflammation or apoptosis as a component. In the nervous system, NF-κB …

Leukocyte apoptosis and its significance in sepsis and shock

DE Wesche, JL Lomas-Neira, M Perl… - Journal of leukocyte …, 2005 - academic.oup.com
… [101] found a significant decrease in apoptosis in patients with systemic inflammatory
response syndrome (SIRS), and the plasma from these patients was able to suppress …

Apoptosis and caspases regulate death and inflammation in sepsis

RS Hotchkiss, DW Nicholson - Nature Reviews Immunology, 2006 - nature.com
shock compared with critically ill patients without sepsis and healthy volunteers 25 . Le … that
lymphocyte apoptosis is rapidly increased in the blood of patients with septic shock, and that …

Upregulation of reactive oxygen species generation and phagocytosis, and increased apoptosis in human neutrophils during severe sepsis and septic shock

PS Martins, EG Kallas, MC Neto, MA Dalboni… - Shock, 2003 - journals.lww.com
… in severe sepsis and septic shock by measuring its phagocytic ability and oxidative burst
activity. We also evaluated neutrophil apoptosis as a regulatory mechanism of the inflammatory

Apoptosis in sepsis

R Mahidhara, TR Billiar - Critical care medicine, 2000 - journals.lww.com
… a model in which apoptosis of neutrophils is delayed when inflammatory signals indicate a
… of neutrophil apoptosis with sepsis is that delays in neutrophil apoptosis may allow for the …

The neuropathology of septic shock

T Sharshar, D Annane, GL de la Gradmaison… - Brain …, 2004 - Wiley Online Library
… the following criteria for septic shock : i) systemic inflammatory response of less than … septic
shock is associated with diffuse cerebral damage and specific autonomic neuronal apoptosis

Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction

RS Hotchkiss, PE Swanson, BD Freeman… - Critical care …, 1999 - journals.lww.com
… regulating the inflammatory response that accompanies sepsis. Much of the tissue injury
occurring in lungs and other organs during sepsis may be caused by uncontrolled inflammation […