The apoptotic pathway as a therapeutic target in sepsis
DE Wesche-Soldato, RZ Swan, CS Chung… - Current drug …, 2007 - ingentaconnect.com
… and normoglycemia affect the inflammatory response and lymphocyte apoptosis. The role of
… either animal sepsis or in vasopressor-dependent septic shock on the onset of apoptosis in …
… either animal sepsis or in vasopressor-dependent septic shock on the onset of apoptosis in …
Cellular apoptosis and organ injury in sepsis: a review
C Power, N Fanning, HP Redmond - Shock, 2002 - journals.lww.com
… Rapid phagocytosis of apoptotic cells in vivo before their secondary degeneration helps
explain the absence of inflammation associated with apoptosis. Apoptotic bodies that escape …
explain the absence of inflammation associated with apoptosis. Apoptotic bodies that escape …
Monocyte anergy in septic shock is associated with a predilection to apoptosis and is reversed by granulocyte-macrophage colony-stimulating factor ex vivo
MA Williams, S Withington, AC Newland… - The Journal of …, 1998 - academic.oup.com
… tional in septic shock, and we hypothesize that this is associated with dysregulated apoptosis.
… regulating inflammation by the inhibition of apoptosis. Normal neutrophils rapidly undergo …
… regulating inflammation by the inhibition of apoptosis. Normal neutrophils rapidly undergo …
Sepsis, apoptosis and complement
PA Ward - Biochemical pharmacology, 2008 - Elsevier
… Septic shock is a major complication of sepsis, usually requiring vasopressor support in …
collectively define a state of unregulated inflammation, together with development of adverse …
collectively define a state of unregulated inflammation, together with development of adverse …
Distinct downstream pathways of caspase-11 in regulating apoptosis and cytokine maturation during septic shock response
SJ Kang, S Wang, K Kuida, J Yuan - Cell Death & Differentiation, 2002 - nature.com
… We provide spatial, temporal and functional evidence that caspase-11 regulates apoptosis
and inflammation in the two downstream pathways that are biochemically separable during …
and inflammation in the two downstream pathways that are biochemically separable during …
Fas-ligand mediated apoptosis in severe sepsis and shock
A Ayala, JL Lomas, PS Grutkoski… - Scandinavian journal of …, 2003 - Taylor & Francis
… inflammatory and apoptotic response in traumatized animals or patients who may be subjected
to several inflammatory/… in septic shock is associated with a predilection to apoptosis and …
to several inflammatory/… in septic shock is associated with a predilection to apoptosis and …
Upregulation of the pro-apoptotic genes BID and FAS in septic shock patients
F Turrel-Davin, C Guignant, A Lepape, B Mougin… - Critical Care, 2010 - Springer
… role in sepsis … apoptosis are so far available in patients. Thus, the aim of our study was to
assess the different biomarkers of apoptosis putatively usable on a routine basis in septic shock…
assess the different biomarkers of apoptosis putatively usable on a routine basis in septic shock…
Septic shock
D Annane, E Bellissant, JM Cavaillon - The Lancet, 2005 - thelancet.com
… systems tightly control the local inflammatory process to eradicate … inflammation occurs,
converting the infection to sepsis, … Cell apoptosis in patients with sepsis varies across cell types. It …
converting the infection to sepsis, … Cell apoptosis in patients with sepsis varies across cell types. It …
Histopathology of septic shock induced acute kidney injury: apoptosis and leukocytic infiltration
N Lerolle, D Nochy, E Guérot, P Bruneval… - Intensive care …, 2010 - Springer
… However, the relevance of these features, notably apoptosis, … kidney lesions associated with
septic shock and their correlation … -mortem kidney sampling in patients dying of septic shock. …
septic shock and their correlation … -mortem kidney sampling in patients dying of septic shock. …
Advances in understanding sepsis
M Shimaoka, EJ Park - European Journal of Anaesthesiology, 2008 - cambridge.org
… in sepsis and techniques to suppress apoptosis have … .), while septic shock is a type of
severe sepsis marked by hypotension … Sepsis is characterized by a surge of the proinflammatory …
severe sepsis marked by hypotension … Sepsis is characterized by a surge of the proinflammatory …