Salidroside protects acute kidney injury in septic rats by inhibiting inflammation and apoptosis

H Fan, B Su, J Le, J Zhu - Drug Design, Development and Therapy, 2023 - Taylor & Francis
… the apoptosis of kidney, we tested the apoptosis of … apoptosis, and inhibited the expression
of pro-apoptotic genes Caspase-3 and Bax mRNA, and increased the expression of apoptosis

… pathophysiologic mechanisms of septic acute kidney injury: role of immune suppression and renal tubular cell apoptosis in murine model of septic acute kidney injury

SY Lee, YS Lee, HM Choi, YS Ko, HY Lee… - Critical care …, 2012 - journals.lww.com
inflammation, apoptosis in septic mice. The role of immune and/or renal tubular cell apoptosis
on septic … , in kidneys of patients who died from septic shock in contrast to patients in the …

Modulation of glucocorticoid receptor expression, inflammation, and cell apoptosis in septic guinea pig lungs using methylprednisolone

K Kamiyama, N Matsuda… - … of Physiology-Lung …, 2008 - journals.physiology.org
… is now considered to play a role in the pathogenesis of septic syndrome. We thus suggest
sepsis-induced cell apoptosis may overwhelm their therapeutic advantages in septic shock. …

The apoptotic response of the lymphoid immune system to trauma, shock, and sepsis

CS Chung, IH Chaudry, A Ayala - Yearbook of Intensive Care and …, 2000 - Springer
… patients were not high enough to induce a septic shock response. Furthermore, the failure of
… The last group of caspases probably play more of a role in inflammation than in apoptosis. …

Apoptosis contributes to septic cardiomyopathy and is improved by simvastatin therapy

U Buerke, JM Carter, A Schlitt, M Russ, H Schmidt… - Shock, 2008 - journals.lww.com
… We propose that among the increasingly recognized anti-inflammatory and … myocardial
depressant substance in humans with septic shock. Septic shock patients with a reduced ejection …

Insights into sepsis therapeutic design based on the apoptotic death pathway

Y Hattori, K Takano, H Teramae… - Journal of …, 2010 - jstage.jst.go.jp
… death in septic patients stems from uncontrolled inflammation. … critical role of cell apoptosis
in the pathophysiology of sepsisapoptosis and inflammation in pathogenesis of septic shock: …

Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity

R Taneja, J Parodo, SH Jia, A Kapus… - Critical care …, 2004 - journals.lww.com
apoptosis in a cohort of critically ill ICU patients with sepsis … clinical inflammation and
experimental inflammation share … , the delayed neutrophil apoptosis of clinical sepsis differs in …

Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients

Y Zhang, J Li, J Lou, Y Zhou, L Bo, J Zhu, K Zhu, X Wan… - Critical care, 2011 - Springer
… clearance, the innate inflammatory response and accelerated apoptosis in sepsis. However,
… cohort of this study thus exhibited a degree of typical apoptosis of septic shock. PD-1 and its …

Immune profile of patients‑a new approach in management of sepsis and septic shock?

A Bacârea, O Coman, VC Bacârea… - Experimental and …, 2024 - spandidos-publications.com
inflammation, termed systemic inflammatory response syndrome, and the presence of a known
infection. It can evolve to septic shock, … in severe sepsis/shock modulates the apoptosis of …

Innate immune molecule surfactant protein D attenuates sepsis-induced acute pancreatic injury through modulating apoptosis and NF-κB-mediated inflammation

Z Liu, Q Shi, J Liu, O Abdel-Razek, Y Xu, RN Cooney… - Scientific reports, 2015 - nature.com
… Inosine reduces systemic inflammation and improves survival in septic shock induced by
cecal ligation and puncture. Am J Respir Crit Care Med 164, 1213–20 (2001). …