… In patients dying of sepsis, both necrotic and apoptotic cell death were observed. Focal …
Extensive apoptotic cell death occurred in lymphocytes and gastrointestinal epithelial cells (…

… apoptotic cell death is an important component of sepsis. In summary, apoptosis occurs
systemically in many types of cells in patients with sepsis and shock. The lymphoid organs and …

… in sepsis is apoptotic death of immune effector cells, including lymphocytes and dendritic cells
(3–9)… patients who died of sepsis showed profound apoptosis-induced depletion of CD4 T …

… is an important mechanism of lymphocyte and gastrointestinal epithelial cell death in sepsis.
… of sepsis on endothelial cell apoptosis in a rat cecal ligation and perforation model of sepsis…

… The recent identification of death factor-receptor pairs that regulate apoptosis brings a new
level of complexity to the understanding of apoptotic cell death. It indicates that an external …

… , as to highlight recent investigations on the critical role of cell apoptosis in the … of the
apoptotic cell death to provide a promising target for the treatment of severe sepsis in …

… is an evolutionarily conserved, energy-dependent mode of cell death requiring the initiation
and regulation of complex genetic programs. It is the body's main method of getting rid of …

… apoptotic cells have on surviving immune cells. This Review focuses on the role of apoptosis
in the pathophysiology of sepsis … Logically, if apoptotic cell death is a major contributor to …

… In addition, apoptosis has been the major focus of cell death in last two decades, but
recently other processes have emerged, eg, pyroptosis, necroptosis, ferroptosis, parthanatos, …

… matched control mice with sepsis. We conclude that both p53-dependent and p53-independent
pathways of cell death exist in sepsis. This differential apoptotic response of thymocytes …