Caffeic acid induces apoptosis in human cervical cancer cells through the mitochondrial pathway

WC Chang, CH Hsieh, MW Hsiao, WC Lin… - Taiwanese Journal of …, 2010 - Elsevier
Caffeic acid is a simple phenolic compound (Figure 1) found primarily in coffee. Studies have
… which caffeic acid inhibits cell proliferation and the pathway of its pro-apoptotic effects are …

Anti-apoptotic activity of caffeic acid, ellagic acid and ferulic acid in normal human peripheral blood mononuclear cells: a Bcl-2 independent mechanism

KL Khanduja, PK Avti, S Kumar, N Mittal… - Biochimica et biophysica …, 2006 - Elsevier
… In conclusion, the anti-apoptotic effect of EA, CA and FA in PBMCs seems to be through the
… anti-apoptotic effects of these dietary compounds on oxidative stress induced apoptosis in …

Antiproliferative and apoptotic effects of caffeic acid on SK-Mel-28 human melanoma cancer cells

LP Pelinson, CE Assmann, TV Palma… - Molecular biology …, 2019 - Springer
… for the first time that caffeic acid has a strong antitumor effect on the SK-Mel-28 melanoma
cell line in vitro, mainly by exerting an antiproliferative and apoptotic effect on these cells and, …

[HTML][HTML] Effect of caffeic acid phenethyl ester on proliferation and apoptosis of colorectal cancer cells in vitro

D Wang, DB Xiang, YJ He, ZP Li, XH Wu… - World journal of …, 2005 - ncbi.nlm.nih.gov
AIM: To study the effect of caffeic acid phenethyl ester (CAPE) on proliferation, cell cycle,
apoptosis and expression of β-catenin in cultured human colorectal cancer (CRC) cell line …

Caffeic acid phenethyl ester‐induced PC‐3 cell apoptosis is caspase‐dependent and mediated through the loss of inhibitors of apoptosis proteins

K McEleny, R Coffey, C Morrissey… - BJU …, 2004 - Wiley Online Library
… We aimed to investigate the effects of CAPE on NF-κB activation and cell death in
prostate cancer cells; we hypothesized that CAPE would induce apoptosis by blocking NF-κB …

Caffeic acid phenethyl ester induces apoptosis of human pancreatic cancer cells involving caspase and mitochondrial dysfunction

MJ Chen, WH Chang, CC Lin, CY Liu, TE Wang… - Pancreatology, 2008 - karger.com
effect of caffeic acid phenethyl ester (CAPE), an active component isolated from honeybee
propolis, in inducing apoptosis … It induced morphological changes of typical apoptosis, but no …

Protective effect of caffeic acid phenethyl ester (CAPE) on myocardial ischemia–reperfusion-induced apoptotic cell death

H Parlakpinar, E Sahna, A Acet, B Mizrak, A Polat - Toxicology, 2005 - Elsevier
… We propose that CAPE acts in the heart as a potent scavenger of free radicals to prevent
the apoptotic effect of I/R. Further studies are needed to elucidate the mechanisms of apoptotic

Inhibitory effect of caffeic acid on cancer cell proliferation by oxidative mechanism in human HT-1080 fibrosarcoma cell line

N Rajendra Prasad, A Karthikeyan… - Molecular and cellular …, 2011 - Springer
… Further, caffeic acid treatment altered the … ), and apoptotic morphological changes in caffeic
acid-treated groups. These data suggest that caffeic acid exhibits potent anticancer effect in …

Protective effect of caffeic acid on paclitaxel induced anti-proliferation and apoptosis of lung cancer cells involves NF-κB pathway

CL Lin, RF Chen, JYF Chen, YC Chu… - International Journal of …, 2012 - mdpi.com
… -apoptotic factor Bid was decreased by CA, indicating the protective effect of CA on PTX-induced
apoptosis … the protective effect of CA on PTX-induced anti-proliferation and apoptosis of …

Caffeic acid phenethyl ester induces mitochondria-mediated apoptosis in human myeloid leukemia U937 cells

UH Jin, KH Song, M Motomura, I Suzuki, YH Gu… - Molecular and cellular …, 2008 - Springer
… It may occur through specific apoptosis … to apoptosis are caused via mitochondrial
pathway. Mitochondria play a crucial role in apoptosis of mammalian cells by releasing pro-apoptotic