Antiproliferative and apoptotic effects of the oxidative dimerization product of methyl caffeate on human breast cancer cells

F Bailly, RA Toillon, O Tomavo, N Jouy… - Bioorganic & medicinal …, 2013 - Elsevier
… Compared to CAPE, apoptosis induced by 1 could be due to … for the antiproliferative and
apoptotic effects. Of note, … the product of the oxidative dimerization of methyl caffeate, 1-…

Neuroprotective effects of methyl caffeate against hydrogen peroxide-induced cell damage: Involvement of caspase 3 and cathepsin D inhibition

D Jantas, J Chwastek, J Malarz, A Stojakowska… - Biomolecules, 2020 - mdpi.com
… This effect was connected with inhibition of apoptotic and necrotic processes induced by
6-OHDA which is in line with our finding from the model of H 2 O 2 -induced cell damage. …

Methyl caffeate and some plant constituents inhibit age-related inflammation: effects on senescence-associated secretory phenotype (SASP) formation

H Lim, BK Park, SY Shin, YS Kwon, HP Kim - Archives of pharmacal …, 2017 - Springer
methyl caffeate, steroid (ophiopogonin), and others like centauroside, rhoifolin and scoparone.
In particular, methyl caffeate … present study demonstrated that methyl caffeate might be a …

In vitro anticancer activity of methyl caffeate isolated from Solanum torvum Swartz. fruit

C Balachandran, N Emi, Y Arun, Y Yamamoto… - Chemico-biological …, 2015 - Elsevier
… The results strongly suggested that methyl caffeate induced apoptosis in MCF-7 cells via …
regulation of mitochondrial apoptosis. Our results indicated that methyl caffeate increased the …

[HTML][HTML] Cytotoxic and apoptotic effects of caffeate derivatives on A549 human lung carcinoma cells

YC Chen, YH Kuo, NC Yang, CW Liu, WT Chang… - Journal of the Chinese …, 2014 - Elsevier
… To reveal the cytotoxic and apoptotic effects of caffeate derivatives, we studied the effects
of octyl, phenylpropyl, and decyl caffeates on cell growth and apoptosis in A549 human lung …

K20E, an oxidative-coupling compound of methyl caffeate, exhibits anti-angiogenic activities through down-regulations of VEGF and VEGF receptor-2

CH Pan, WH Lin, YC Chien, FC Liu, MJ Sheu… - Toxicology and applied …, 2015 - Elsevier
… Thus, the expression levels of p53-p21 pathway controlling the cell cycle arrest and
apoptosis were also analyzed in the present study. The experimental results showed that the …

Bornyl caffeate induces apoptosis in human breast cancer MCF-7 cells via the ROS-and JNK-mediated pathways

C Yang, W Pei, J Zhao, Y Cheng, X Zheng… - Acta Pharmacologica …, 2014 - nature.com
… To explore the mechanisms modulating the induction of apoptosis, we investigated the effect
of bornyl caffeate on different protein kinases. MCF-7 cells were treated with bornyl caffeate

Protective Effect of Phenolic Compounds Isolated from Mugwort (Artemisia argyi) against Contrast-Induced Apoptosis in Kidney Epithelium Cell Line LLC-PK1

KO Kim, D Lee, NT Hiep, JH Song, HJ Lee, D Lee… - Molecules, 2019 - mdpi.com
… were carried out with methyl caffeate, since it represented … Effect of Methyl Caffeate on
Iodixanol-Induced Apoptosis and … methyl caffeate could reduce iodixanol-induced apoptosis in LLC…

Chemical Components of the Fruits of Morus nigra Linn.: Methyl Caffeate as a Potential Anticancer Agent by Targeting 3-Phosphoglycerate Dehydrogenase

Y Wang, M Zheng, Q Jiang, Y Xu, X Zhou… - Journal of Agricultural …, 2021 - ACS Publications
… Among these compounds, methyl caffeate (3) exhibited effective inhibition against PHGDH
… expressing cancer cell lines and could cause apoptosis of cervical cancer cells in micromolar …

Phenethyl caffeate benzo [kl] xanthene lignan with DNA interacting properties induces DNA damage and apoptosis in colon cancer cells

V Vijayakurup, S Carmela, D Carmelo, T Corrado… - Life sciences, 2012 - Elsevier
… induction of DNA damage and apoptosis. In order to … , methyl caffeate benzoxanthene
lignan, MCBL) was also included in the present study. MCBL differs from PCBL in bearing methyl