[HTML][HTML] Overexpression of TGFβ1 in murine mesenchymal stem cells improves lung inflammation by impacting the Th17/Treg balance in LPS-induced ARDS mice

J Chen, X Zhang, J Xie, M Xue, L Liu, Y Yang… - Stem Cell Research & …, 2020 - Springer
… of CD4 + T cells, but the … , mouse MSCs (mMSCs) overexpressing TGFβ1 were constructed
by lentivirus transduction and intratracheally transplanted into LPS-induced ARDS mice in …

[HTML][HTML] The effect of human adipose-derived stem cells on lipopolysaccharide-induced acute respiratory distress syndrome in mice

YJ Jung, YY Park, JW Huh, SB Hong - Annals of translational …, 2019 - ncbi.nlm.nih.gov
… In this study, we investigated the effects of human ASCs in an LPS-induced ARDS mouse
model, as well as the relevant inflammatory factors and histological changes. The injection of …

Mesenchymal stem cells: mechanisms of potential therapeutic benefit in ARDS and sepsis

J Walter, LB Ware, MA Matthay - The Lancet Respiratory Medicine, 2014 - thelancet.com
… of both acute respiratory distress syndrome (ARDS) and sepsis. Although initial research …
mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice

[HTML][HTML] Overexpressing p130/E2F4 in mesenchymal stem cells facilitates the repair of injured alveolar epithelial cells in LPS-induced ARDS mice

X Zhang, J Chen, M Xue, Y Tang, J Xu, L Liu… - Stem cell research & …, 2019 - Springer
… E2F4 in mMSCs could further improve the injured structure and function of epithelial cells in
the lungs of ARDS mice as a result of improved differentiation of mMSCs into epithelial cells. …

[HTML][HTML] Therapeutic mechanisms of mesenchymal stem cells in acute respiratory distress syndrome reveal potentials for Covid-19 treatment

W Wang, W Lei, L Jiang, S Gao, S Hu, ZG Zhao… - Journal of translational …, 2021 - Springer
… Mesenchymal stem cells (MSCs) can be derived from bone … that mesenchymal stem cell
infusion can ameliorate ARDS. … in LPS-induced ARDS mouse models and reducing neutrophil …

[HTML][HTML] Mesenchymal stem cells: current clinical progress in ARDS and COVID-19

K Xiao, F Hou, X Huang, B Li, ZR Qian, L Xie - Stem Cell Research & …, 2020 - Springer
… Because stem cells are resistant to tissue damage, promote tissue … stem cells is bringing
hope for a treatment for respiratory virus-induced pneumonia [25]. In the H9N2-infected mouse

[HTML][HTML] Mesenchymal stem cells with downregulated Hippo signaling attenuate lung injury in mice with lipopolysaccharide‑induced acute respiratory distress …

L Li, L Dong, J Zhang, F Gao… - … Journal of Molecular …, 2019 - spandidos-publications.com
… into ARDS mice via the airway, and then, these mMSCs were evaluated for their retention
in ARDS lung tissue, differentiation into ATII cells and capacity for repairing lung injury. …

Strategies to enhance mesenchymal stem cell‐based therapies for acute respiratory distress syndrome

J Han, Y Li, Y Li - Stem cells international, 2019 - Wiley Online Library
… years, cell therapy has been introduced in preclinical ARDS studies. A variety of cell types
… in the mice treated with Del-1-expressed MSCs than in the mice treated with MSCs alone. …

Mesenchymal stem cells: a promising therapy for the acute respiratory distress syndrome

N Cárdenes, E Cáceres, M Romagnoli, M Rojas - Respiration, 2013 - karger.com
… definition of ARDS and the … old mouse with declining organ stem cell capacity underwent
rejuvenation of aged muscle and liver progenitor cells when surgically joined to a young mouse

Mesenchymal stem cells inhibited the apoptosis of alveolar epithelial cells caused by ARDS through CXCL12/CXCR4 axis

X He, C Li, H Yin, X Tan, J Yi, S Tian, Y Wang… - …, 2022 - Taylor & Francis
… , and an LPS-induced ARDS mouse model by tail vein … on ARDS cell apoptosis. We found
for the first time that MSCs inhibited the apoptosis of alveolar epithelial cells caused by ARDS