[HTML][HTML] Arginine metabolism and its potential in treatment of colorectal cancer
T Du, J Han - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
… arginine metabolism and its role in diagnosis and therapy for colorectal cancer, this review
discusses arginine metabolism … its transporters in colorectal cancer. Although the literature on …
discusses arginine metabolism … its transporters in colorectal cancer. Although the literature on …
[HTML][HTML] L-Arginine/NO pathway metabolites in colorectal cancer: relevance as disease biomarkers and predictors of adverse clinical outcomes following surgery
I Bednarz-Misa, MG Fleszar, M Zawadzki… - Journal of Clinical …, 2020 - mdpi.com
… Metabolic reprogramming has been recognized as one of … , arginine and citrulline accumulation
in colorectal cancer tissue… Arginine has been repeatedly shown to facilitate tumor growth, …
in colorectal cancer tissue… Arginine has been repeatedly shown to facilitate tumor growth, …
[HTML][HTML] Arginine signaling and cancer metabolism
… In this review, we will discuss arginine as a signaling metabolite, arginine’s role in cancer …
characterizing arginine-deprived cancer cells, we will also update the current status of arginine…
characterizing arginine-deprived cancer cells, we will also update the current status of arginine…
[HTML][HTML] The effect of arginine intake on colorectal cancer: a systematic review of literatures
J Karimian, A Hadi… - Clinical Nutrition …, 2019 - synapse.koreamed.org
Colorectal cancer (CRC) is one of the major reasons … arginine can improve CRC and its
complications. Hence, in this systematic review we evaluated the association between arginine …
complications. Hence, in this systematic review we evaluated the association between arginine …
[HTML][HTML] Arginine metabolism and cancer
VL Albaugh, C Pinzon-Guzman… - Journal of surgical …, 2017 - ncbi.nlm.nih.gov
… Moreover, in one model of murine colorectal cancer, arginine supplementation decreased
tumor incidence and overall tumor burden when supplemented early in the disease course. …
tumor incidence and overall tumor burden when supplemented early in the disease course. …
Inhibition or promotion, the potential role of arginine metabolism in immunotherapy for colorectal cancer
C Chen, X Jiang, Z Zhao - All Life, 2023 - Taylor & Francis
… In addition, the role of arginine metabolism in the immunotherapy of CRC is still … of arginine
metabolism in CRC, this paper reviews the molecular mechanisms of arginine metabolism in …
metabolism in CRC, this paper reviews the molecular mechanisms of arginine metabolism in …
Targeting arginine metabolism pathway to treat arginine-dependent cancers
F Qiu, J Huang, M Sui - Cancer letters, 2015 - Elsevier
… , MM and prostate cancer and partially deficient in breast cancer, renal cancer and sarcoma,
while it was highly expressed in colorectal cancer, gastric cancer and lung squamous cell …
while it was highly expressed in colorectal cancer, gastric cancer and lung squamous cell …
[HTML][HTML] Sensitivity of colorectal cancer to arginine deprivation therapy is shaped by differential expression of urea cycle enzymes
C Alexandrou, SS Al-Aqbi, JA Higgins, W Boyle… - Scientific reports, 2018 - nature.com
… arginine and can be targeted using arginine-deprivation therapy. Here, we show that colorectal
cancers (… determined by endogenous levels of arginine metabolic enzymes. Cell Biol Int …
cancers (… determined by endogenous levels of arginine metabolic enzymes. Cell Biol Int …
[HTML][HTML] Overexpression of arginine transporter CAT-1 is associated with accumulation of L-arginine and cell growth in human colorectal cancer tissue
Y Lu, W Wang, J Wang, C Yang, H Mao, X Fu, Y Wu… - PloS one, 2013 - journals.plos.org
… that L-arginine (Arg) accumulates in colorectal cancer tissues. … sera and tumor tissues from
colorectal cancer (CRC) patients … Our results indicated that Arg metabolism is accelerated in …
colorectal cancer (CRC) patients … Our results indicated that Arg metabolism is accelerated in …
[HTML][HTML] Arginine Is a Novel Drug Target for Arginine Decarboxylase in Human Colorectal Cancer Cells
X Wei, HY Chow, HC Chong, SL Leung, MK Ho… - International Journal of …, 2023 - mdpi.com
… A study has shown that agmatine accumulates in colorectal cancer cells without being
metabolized, and inhibits cell proliferation by reducing cellular polyamine levels [37]. Consistent …
metabolized, and inhibits cell proliferation by reducing cellular polyamine levels [37]. Consistent …
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