… We conclude that residue 183 contributes to the binding of aromatic hydroxyphosphonates
to IMPase, but it is not the only determining factor for inhibitor specificity with respect to …

… ‐, d‐chiro‐, and scyllo‐) and derivatives rarer or thought not to exist in nature. However, neo‐
and d‐chiro‐inositol … , scyllo‐inositol (neurodegenerative diseases) and d‐chiro‐inositol (…

… 16 The other product was the aromatic phosphonate 7. … We conclude, therefore, that
disubstitution of phosphonate groups for the 4.5-phosphates greatly reduces the efficacy of inositol …

… -inositol 1,3,4_trisphosphate (Ins[l,3,4]P3)‘, which is also degraded to myo-inositol. The …
As part of a programme on the synthesis of myo-inositol phosphates and analogues thereof ‘…

… myo-inositol derivatives which are not metabolized by enzymes. Phosphorothioate, phosphonate
and other analogs have been synthesized as enzyme-resistant analogs of myo-inositol …

… They have been shown to contain myo- or chiro-inositol, phosphate, D-… Therefore, a compound
containing a cyclic phosphonate … Modest amounts of D-chiroinositol can be obtained by …

… In this paper, 12 mono-phosphonate inositol compounds were prepared … of inositol
phosphonate analogues using myo-inositol as the starting material, and found that two phosphonate …

… (36) of 3-phosphorylated myoinositol phospholipids and their … (phosphonate)(230) is reported
to be a highly selective host for aromatic guanidinium ions¹99 and the crown phosphonate (…

… They proposed that one phosphonate mimics the phosphate … Alternatively, both phosphonates
may interact equally, each … against mlPase with aromatic bisphosphonic acid derivatives …

… inositol (if the stereoisomer of inositol is not explicitly stated, it should be assumed to be
myo-inositol… describe the orientation of the hydroxyl groups in myoinositol (Figure 2), likening the …