… arrest within mitochondria, either directly or indirectly, is difficult to approach in vivo with the
intact embryo… the major proteins encoded by the mitochondrial genome are few in number, …

… mitochondria are found in normal cleaving embryos, the mitochondria from developmentally
arrested embryos … The mitochondrial genetic bottleneck is one of the most important …

… % of arrested or fragmented embryos, and 21.1% of 3PN embryos … , ND6 and Cyt b genes in
oocytes and embryos revealed that the … oocytes than in arrested embryos and 3PN embryos. …

… Since the level of mtDNA remains the same up to the blastocyst stage, the authors
conclude that there exists an arrest of mtRNA synthesis in early embryos and that the steady-state …

… Embryos in homozygous seeds were arrested at the globular stage … that the mitochondrial
GCP1 is essential for embryonic … in mitochondrial genome maintenance was proposed [12]. …

… mitochondrial genes that affect many aspects of embryo development and survival, but excludes
those genes … functional mitochondria leading to embryonic arrest, failed implantation, or …

… mouse NRF-1 gene leads to embryonic death around the time of … As examples, the stage of
developmental arrest has been … Interestingly, the timing of this arrest coincides approximately …

… We hypothesize that early embryonic arrest is triggered by gene expression associated with
… that trigger mitochondrial apoptosis [44]. We do not know whether the elevated ROS and …

… Moreover, all embryos in this ST group arrested before reaching blastocysts, whereas 57%
controls progressed to blastocysts. These ST results were similar to those seen with frozen-…

… if fertilized, a higher frequency of arrested or abnormal embryonic development during the
early … Morphological, cytochemical and molecular genetic analysis of mitochondria in isolated …