miRNA delivery by nanosystems: state of the art and perspectives

FC Moraes, C Pichon, D Letourneur, F Chaubet - Pharmaceutics, 2021 - mdpi.com
miRNA or miRNA expression vectors to induce expression of a miRNA in cells and the delivery
of the miRNA … to restore miRNA levels using synthetic double-stranded miRNAs to mimic …

Recent advances in miRNA delivery systems

I Dasgupta, A Chatterjee - Methods and protocols, 2021 - mdpi.com
… Here, we highlight the strengths and weaknesses of current state-of-the-art viral and non-viral
miRNA delivery systems and provide perspective on how these tools can be exploited to …

The challenges and opportunities in the development of MicroRNA therapeutics: a multidisciplinary viewpoint

MY Momin, RR Gaddam, M Kravitz, A Gupta, A Vikram - Cells, 2021 - mdpi.com
microRNAs (miRs) are emerging as attractive therapeutic … , cell type-specific delivery, and
adverse outcomes have … inhibitors, and innovative delivery approaches have helped resolve …

Nanomedicines to deliver mRNA: state of the art and future perspectives

I Gómez-Aguado, J Rodríguez-Castejón… - Nanomaterials, 2020 - mdpi.com
… Indeed, they are clinically validated delivery systems for RNA therapy. In the beginning, LNPs
were considerably promising for the delivery of siRNA, being their utility as mRNA delivery

[HTML][HTML] MicroRNA delivery systems in glioma therapy and perspectives: A systematic review

JM Jiménez-Morales, YE Hernández-Cuenca… - Journal of Controlled …, 2022 - Elsevier
… Thus, the present systematic review aimed to analyze the current status of miRNA delivery
system use and to identify promising therapeutic approaches for future clinical and research …

[HTML][HTML] Repairing the heart: State-of the art delivery strategies for biological therapeutics

Q Yang, J Fang, Z Lei, JPG Sluijter… - Advanced Drug Delivery …, 2020 - Elsevier
perspective on therapeutic approaches using genes, mRNA and proteins for cardiac repair
using synthetic delivery … molecules as well, including microRNAs and Extracellular vesicles […

Micro-RNAs and ovarian cancer: the state of art and perspectives of clinical research

A Gadducci, C Sergiampietri, N Lanfredini… - Gynecological …, 2014 - Taylor & Francis
Dysregulation of microRNA (mi-RNA) expression plays a major role in the development and
progression of most human malignancies. Members of the miR-200 family, miR-182, miR-…

MicroRNA delivery through nanoparticles

SWL Lee, C Paoletti, M Campisi, T Osaki… - Journal of Controlled …, 2019 - Elsevier
delivery of miRNAs for therapeutic purposes. This review critically discusses the use of
nanoparticles for the delivery of miRNA-… A fresh perspective is presented on the design and …

MicroRNAs and their big therapeutic impacts: delivery strategies for cancer intervention

C Holjencin, A Jakymiw - Cells, 2022 - mdpi.com
… As such, in this review, we discuss the strengths and weaknesses of the current state-of-the-art
delivery systems, encompassing viral- and nonviral-based systems, with a specific focus …

Exosomal chaperones and miRNAs in gliomagenesis: State-of-art and theranostics perspectives

C Caruso Bavisotto, F Graziano, F Rappa… - International Journal of …, 2018 - mdpi.com
… of exosomal chaperones and miRNAs in gliomagenesis. Chaperones may … miRNAs (the
latter possibly related to chaperone gene expression in the recipient cell), and probably deliver