Therapeutic angiogenesis for peripheral artery disease: lessons learned in translational science

SR Iyer, BH Annex - Basic to translational science, 2017 - jacc.org
Peripheral arterial disease (PAD) is a major health care problem. There have been limited
advances in medical therapies, and a huge burden of symptomatic patients with intermittent …

Translational research in coronary artery disease

WS Aronow, JA McClung, M Limbert, N Abraham - 2016 - Elsevier
artery disease. In so doing, it will elaborate our current understanding of endothelial cell
turnover, the various factors that modify it, and the opportunities for both further research on and …

Bench-to-bedside in vascular medicine: optimizing the translational pipeline for patients with peripheral artery disease

T Alsaigh, BA Di Bartolo, J Mulangala… - Circulation …, 2021 - Am Heart Assoc
… Peripheral arterial disease is a growing worldwide problem with a wide spectrum of clinical
severity and is projected to consume >$21 billion per year in the United States alone. While …

Translational atherosclerosis research: From experimental models to coronary artery disease in humans

CA Gleissner - Atherosclerosis, 2016 - Elsevier
… Eg in Germany, over the past two decades, mortality from coronary artery disease could
be reduced by 28%. Mortality of acute myocardial infarction even decreased by 40% (“Heart …

[HTML][HTML] Translational Science in Vascular Aging: From Bench to Bedside—Insights from a VascAgeNet Roundtable

E Bianchini, L Roth, P Boutouyrie, S Badhwar… - Artery Research, 2024 - Springer
Translational science offers a pathway to overcome these … It covers the translation of findings
from basic science to … at the Artery 23 conference, focusing on the translational process in …

[图书][B] Translational research in coronary artery disease: pathophysiology to treatment

WS Aronow, JA McClung - 2015 - books.google.com
… These first years of the new millennium have witnessed an explosion in translational research
in the field of cardiovascular disease in general and coronary artery disease in particular. …

Genetics of coronary artery disease: discovery, biology and clinical translation

AV Khera, S Kathiresan - Nature Reviews Genetics, 2017 - nature.com
… Observational epidemiology and translational research efforts have led to significant progress
in improving the understanding of the pathophysiology underlying coronary artery disease

[HTML][HTML] Imaging of small animal peripheral artery disease models: recent advancements and translational potential

JB Lin, EH Phillips, TAE Riggins, GS Sangha… - … of molecular sciences, 2015 - mdpi.com
… Peripheral artery disease (PAD) is a broad disorder encompassing multiple forms of arterial
disease outside of the heart. As such, PAD development is a multifactorial process with a …

SVEP1 is a human coronary artery disease locus that promotes atherosclerosis

IH Jung, JS Elenbaas, A Alisio, K Santana… - Science translational …, 2021 - science.org
… associated with coronary artery disease (CAD) (10). At most loci, however, the causal gene
is unknown, presenting a major bottleneck and hindering the translation of these findings into …

[HTML][HTML] Recent advances in treatment of coronary artery disease: role of science and technology

E Kandaswamy, L Zuo - International journal of molecular sciences, 2018 - mdpi.com
scientific advancements in the understanding of the pathophysiology of coronary artery
disease (… on the recent advances in coronary artery disease research in respect to therapeutics …