Lymph draining from foot joints in rheumatoid arthritis provides insight into local cytokine and chemokine production and transport to lymph nodes

WL Olszewski, J Pazdur, E Kubasiewicz… - Arthritis & …, 2001 - Wiley Online Library
lymphatic system, is unclear. To determine which inflammatory factors produced in the joints
of RA patients are transported in lymph to lymph nodes… prenodal lymph from the foot joints of …

In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice

EM Bouta, RW Wood, EB Brown… - The Journal of …, 2014 - Wiley Online Library
… could be involved in arthritic flare that have yet to be investigated are changes in viscosity
and pressure within lymphatic vessels and lymph nodes efferent to inflamed joints. In the case …

Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis

EM Bouta, RD Bell, H Rahimi, L Xing… - Nature Reviews …, 2018 - nature.com
… of the synovial lymphatic system in the context of joint homeostasis and inflammatory arthritis,
… As outlined in this Review, the discovery that altered lymph node dynamics and lymphatic

CCR4 and CXCR3 play different roles in the migration of T cells to inflammation in skin, arthritic joints, and lymph nodes

NA Al‐Banna, M Vaci, D Slauenwhite… - European Journal of …, 2014 - Wiley Online Library
… into inflamed joints in collagen-induced arthritis, antigen-draining lymph nodes (LNs) and …
Both CXCR3 and CCR4 deficiency reduced the development of arthritis, but did not affect …

The role of the lymphatic system in inflammatory-erosive arthritis

EM Bouta, J Li, Y Ju, EB Brown, CT Ritchlin… - Seminars in cell & …, 2015 - Elsevier
… One apparent contradiction with our findings regarding PLN as a biomarker of inflammation
in the adjacent joint is that the knee drains to the iliac lymph node (ILN), while the ankle …

Distribution of lymphatic vessels in normal and arthritic human synovial tissues

H Xu, J Edwards, S Banerji, R Prevo… - Annals of the …, 2003 - ard.bmj.com
… of lymphangiogenesis which has been identified in the hypertrophic synovium of arthritic
joints. … fluid and leucocyte trafficking to lymph nodes rather than a lack of lymphatic vessels. …

Lymph nodes in rheumatoid arthritis

AG MOTULSKY, S WEINBERG… - AMA archives of …, 1952 - jamanetwork.com
… on the coincidence of rheumatoid arthritis and giant follicular … lymph node pathology in
patients with rheumatoid arthritis … enlarged lymph nodes, and a marked improvement of the joint

[HTML][HTML] Increased lymphangiogenesis in joints of mice with inflammatory arthritis

Q Zhang, Y Lu, ST Proulx, R Guo, Z Yao… - Arthritis research & …, 2007 - Springer
… vessel numbers and size were markedly increased in joint sections of TNF-Tg mice and
mice with serum-induced arthritis. The severity of synovitis correlated with draining lymph node

MRI and quantification of draining lymph node function in inflammatory arthritis

ST Proulx, E Kwok, Z You, CA Beck… - Annals of the New …, 2007 - Wiley Online Library
… estimation of the drainage potential of a lymph node. This approach also has the advantages
of … As the popliteal lymph node drains both the knee and the ankle joints, 33 it is certain that …

Restricted heterogeneity in T-cell antigen receptor V beta gene usage in the lymph nodes and arthritic joints of mice.

TM Haqqi, GD Anderson… - Proceedings of the …, 1992 - National Acad Sciences
joints and lymph nodes of B1O.Q mice (H-2r) immunized with chicken type II collagen. Our
data show that the T cells present in arthritic joints … In lymph node cells, transcripts for $j6,-8.2, …