Quantitative analysis of gene expression in human articular cartilage from normal and osteoarthritic joints

I Martin, M Jakob, D Schäfer, W Dick, G Spagnoli… - … and Cartilage, 2001 - Elsevier
… -time PCR assays to quantify gene expression in human cartilage tissue. The method allows
quantification of levels of ECM gene expression averaged among all cartilage layers, and is …

Comparison of gene expression patterns in articular cartilage and dedifferentiated articular chondrocytes

T Cheng, NC Maddox, AW Wong… - Journal of …, 2012 - Wiley Online Library
… We sought to identify an extended pattern of gene expression to define the phenotype of
articular cartilage since previous studies have used heterogeneous methods with variable …

Zone‐specific gene expression patterns in articular cartilage

SP Grogan, SF Duffy, C Pauli, JA Koziol… - Arthritis & …, 2013 - Wiley Online Library
… permuted samples or gene lists (45). Only the RMA-normalized data obtained from …
articular cartilage was used for the GSEA; we filtered out any genes with maximal expression

Zonal and topographical differences in articular cartilage gene expression

EM Darling, JCY Hu… - Journal of orthopaedic …, 2004 - Wiley Online Library
… The differences in gene expression are quantified in this study to show that … an articular
cartilage engineering study. In addition to measuring the zonal differences of articular cartilage, …

[HTML][HTML] Reference genes for normalization of gene expression studies in human osteoarthritic articular cartilage

M Pombo-Suarez, M Calaza, JJ Gomez-Reino… - BMC molecular …, 2008 - Springer
… The prospective reference genes included in this study covered a wide range of expression
levels in articular cartilage (mean Ct values ranging from 18 to 36). Results from individual …

[HTML][HTML] Gene expression changes in damaged osteoarthritic cartilage identify a signature of non-chondrogenic and mechanical responses

SL Dunn, J Soul, S Anand, JM Schwartz… - … and cartilage, 2016 - Elsevier
… Joint degeneration in osteoarthritis (OA) is characterised by damage and loss of articular
cartilage. The pattern of loss is consistent with damage occurring only where the mechanical …

Gene expression profiling of human articular cartilage grafts generated by tissue engineering

C Kaps, S Frauenschuh, M Endres, J Ringe, A Haisch… - Biomaterials, 2006 - Elsevier
… In this study autologous human cartilage tissue engineering grafts based on … articular
chondrocytes and from three-dimensional cartilage grafts were used for gene expression

[HTML][HTML] Gene expression during redifferentiation of human articular chondrocytes

T Tallheden, C Karlsson, A Brunner… - … and cartilage, 2004 - Elsevier
… The aim of the present study was to investigate gene expression during the in vitro
redifferentiation process of human articular chondrocytes isolated from clinical samples from patient …

Temporal effects of impact on articular cartilage cell death, gene expression, matrix biochemistry, and biomechanics

RM Natoli, CC Scott, KA Athanasiou - Annals of biomedical engineering, 2008 - Springer
… taking place in articular cartilage cell viability, gene expression, matrix … articular cartilage to
mechanical injury, as occurring in our system, and (2) investigate differential gene expression

Load-controlled compression of articular cartilage induces a transient stimulation of aggrecan gene expression

WB Valhmu, EJ Stazzone, NM Bachrach… - Archives of Biochemistry …, 1998 - Elsevier
… This is due in part to the fact that the dense cartilage … the study of gene expression of specific
cartilage matrix components in … stimulation of aggrecan gene expression in response to …