Load-controlled compression of articular cartilage induces a transient stimulation of aggrecan gene expression

WB Valhmu, EJ Stazzone, NM Bachrach… - Archives of Biochemistry …, 1998 - Elsevier
… expression of specific cartilage matrix components in response to applied stimuli at any
time during the loading regime. In this study, we identified a transient stimulation of aggrecan …

Differential responses of chondrocytes from normal and osteoarthritic human articular cartilage to mechanical stimulation

DM Salter, SJ Millward‐Sadler, G Nuki… - …, 2002 - content.iospress.com
… Mechanical stimulation is critically important for the maintenance of normal articular cartilage
… Ratcliff, Load-controlled compression of articular cartilage induces a transient stimulation of …

Toward regeneration of articular cartilage

M Iwamoto, Y Ohta, C Larmour… - … Research Part C …, 2013 - Wiley Online Library
… Thus, stimulation of articular cartilage repair and regeneration of … will review how articular
cartilage is distinct from transient growth plate cartilage, how articular cartilage develops and …

Physicochemical and biomechanical stimuli in cell-based articular cartilage repair

H Jahr, C Matta, A Mobasheri - Current rheumatology reports, 2015 - Springer
… Several physicochemical and biomechanical stimuli are reported to influence chondrocyte …
most relevant stimuli and describe how ion channels may contribute to cartilage homeostasis, …

Altered electrophysiological responses to mechanical stimulation and abnormal signalling through α5β1 integrin in chondrocytes from osteoarthritic cartilage

SJ Millward-Sadler, MO Wright, HS Lee… - … and cartilage, 2000 - Elsevier
… Compression of articular cartilage by mechanical forces is … Experimental mechanical stimulation
of articular cartilage explants and … of articular cartilage induces a transient stimulation of …

Effects of electrical stimulation on articular cartilage regeneration with a focus on piezoelectric biomaterials for articular cartilage tissue repair and engineering

Z Zhou, J Zheng, X Meng, F Wang - International Journal of Molecular …, 2023 - mdpi.com
… ES is a very effective stimulator to promote cartilage growth and repair. ES initiates cell
differentiation by activating calcium transients to activate calmodulin and its downstream signals […

Biophysical stimuli: a review of electrical and mechanical stimulation in hyaline cartilage

JJ Vaca-González, JM Guevara, MA Moncayo… - Cartilage, 2019 - journals.sagepub.com
… approaches for the treatment of injuries in articular cartilage and growth plate. In this …
stimulation over chondrocytes intended for articular cartilage recovery and the mechanical stimuli

A novel method for determining articular cartilage chondrocyte mechanics in vivo

Z Abusara, R Seerattan, A Leumann, R Thompson… - Journal of …, 2011 - Elsevier
… multi-photon microscopy with controlled electrical stimulation of the knee extensor muscles.
… , and our observations were made under transient, dynamic conditions while previous ex …

Effect of strain rate on transient local strain variations in articular cartilage

A Komeili, Z Abusara, S Federico, W Herzog - Journal of the Mechanical …, 2019 - Elsevier
… of articular cartilage have been measured primarily for static conditions, but the dynamic
properties are thought to be more relevant for joint function and cartilage … of articular cartilage for …

Basic FGF mediates an immediate response of articular cartilage to mechanical injury

T Vincent, M Hermansson, M Bolton… - Proceedings of the …, 2002 - National Acad Sciences
… Our findings also raise the possibility that bFGF plays a homeostatic role in articular cartilage.
Exaggerated … As expected, stimulation of chondrocytes with medium conditioned by recut …