Plasma Ptau181 to Aβ42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant …

JR Chong, NJ Ashton, TK Karikari… - Alzheimer's & …, 2021 - Wiley Online Library
P-tau181 and P-tau217 in plasma using the same assay technology and in the same cohort,
are … In conclusion, we showed that plasma P-tau181 and Aβ measurements in an Asian

[HTML][HTML] Plasma p-tau181 level predicts neurodegeneration and progression to Alzheimer's dementia: a longitudinal study

YL Wang, J Chen, ZL Du, H Weng, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
… As for the cohort, plasma p-tau181 was significantly associated with CSF Aβ and above
biomarkers (Supplementary Table 1). Figure 3 indicates that there may be non-linear …

[HTML][HTML] Plasma β-amyloid, tau, neurodegeneration biomarkers and inflammatory factors of probable Alzheimer's disease dementia in Chinese individuals

Q Sun, J Ni, M Wei, S Long, T Li, D Fan, T Lu… - Frontiers in Aging …, 2022 - frontiersin.org
… Aβ42/Aβ40 ratio was significantly declined and the levels of the plasma p-tau181, NfL
and TNF-α were significantly higher in the AD group than the NC group, but there was no …

[HTML][HTML] Plasma biomarkers predict Alzheimer's disease before clinical onset in Chinese cohorts

H Cai, Y Pang, X Fu, Z Ren, L Jia - Nature Communications, 2023 - nature.com
plasma Aβ42, p-tau181, and NfL may be useful for predicting AD 8 years before clinical onset
in Chinese … In this study, we measure the plasma levels of Aβ40, Aβ42, p-tau181, t-tau, and …

[HTML][HTML] Reference intervals for plasma amyloid-β, total tau, and phosphorylated tau181 in healthy elderly Chinese individuals without cognitive impairment

J Chen, X Zhao, W Zhang, T Zhang, S Wu… - Alzheimer's Research & …, 2023 - Springer
… Here, we provide a detailed description of the changes in plasma Aβ, t-tau, and p-tau181 in
healthy elderly Chinese individuals without cognitive impairment using ultrasensitive Simoa …

The diagnostic value of plasma phosphorylated tau 181 in AD within the Chinese population: A systematic review and meta-analysis

K Yan, S He, X Jia, H Li, D Liu, J Chen - medRxiv, 2024 - medrxiv.org
Plasma p-tau181 levels in healthy cohorts 164 A summary of plasma p-tau181 levels in
Chinese healthy cohorts was presented. Subgroup analysis was performed according to age …

Predicting amyloid PET positivity using plasma ptau181 and other blood‐based biomarkers

HS Kwon, EH Lee, HJ Kim, SH Park… - Alzheimer's & …, 2023 - Wiley Online Library
… is lacking, especially in Asians. Here, we investigated the … different combinations of plasma
biomarkers (p-tau181, NfL, … BioFINDER-2 cohort showed higher plasma p-tau181 level (mean …

[HTML][HTML] The dynamics of plasma biomarkers across the Alzheimer's continuum

Y Guo, XN Shen, HF Wang, SD Chen… - Alzheimer's Research & …, 2023 - Springer
plasma p-tau181 as an AD blood biomarker [9, 16, 36,37,38,39,40]. As a proof-of-principle,
our plasma p-tau181 assay in Chinese … prove the reliability of our findings in Chinese cohorts. …

Plasma p‐tau217, ptau181, and NfL as early indicators of dementia risk in a community cohort: The Shanghai Aging Study

Z Xiao, W Wu, X Ma, J Wu, X Liang… - Alzheimer's & …, 2023 - Wiley Online Library
cohort study conducted in the Chinese population with a comparable study design and
procedures to most epidemiological cohort … of baseline plasma p-tau217, p-tau181, and NfL in …

Plasma Aβ42/Aβ40 and p-tau181 predict long-term clinical progression in a cohort with amnestic mild cognitive impairment

Z Xiao, W Wu, X Ma, X Liang, J Lu, L Zheng… - Clinical …, 2022 - academic.oup.com
… that a simplified model combining plasma p-tau181, Aβ42, and … In the current study based
on our clinical cohort, we analyzed … All the neuropsychological tests were in Chinese, and the …