… cancer has been increasing in Asia. Be cause Asian patients develop breast cancer at a …
, the contributions of BRCA1 and BRCA2 (BRCA1/2) mutations in Asians are expected to be …

… of carrying a pathogenic variant in BRCA1 or BRCA2 gene, using germline BRCA genetic
… Asian patients with breast cancer. We compared the model performance to existing mutation …

… other Asian countries mainly in Central and Western Asia. We present the current pathogenic
mutation spectrum of BRCA1/BRCA2 genes in patients with breast cancer in various Asian …

… mutations are more common among ovarian cancer cases than BRCA2 mutations, although
the ratio of BRCA1 to BRCA2 … as many BRCA1 as BRCA2 mutations, respectively, whilst in a …

… BRCA2 mutations among Malaysian ovarian cancer patients suggest that healthcare
professionals responsible for the care of ovarian cancer patients … all ovarian cancer patients in …

… , and evaluation of missense mutations of unknown clinical … the prevalence of BRCA1/BRCA2
mutations, to our knowledge… testing strategy for BRCA1 and BRCA2 mutation detection. …

… These necessitate a rigorous review of BRCA1/BRCA2 mutations in this region. Thus, this …
BRCA2 gene mutations and explore the spectrum of these mutations among the South Asian …

… patients with either BRCA1 or BRCA2 mutations were significantly younger than ER-positive
patients… that our TNBC patients with either BRCA1 or BRCA2 mutations were diagnosed at …

… were developed based on mutation rates observed primarily in … in Asia or in Asians living
elsewhere. Here, we report the results of genetic testing for mutations in the BRCA1 or BRCA2 …

… testing in Asian countries … mutations in our Asian populations. In this study, we designed
a genotyping assay with 55 BRCA1 and 44 BRCA2 mutations previously identified in Asian …